QuickView for DLgr2;jsessionid=7B3880E91912E784705D2B6AE40F6AC1;jsessionid=1F2CA468775AAC7E7B4D00D486A2209E;jsessionid=1BBB75A0387D86A097164FD10467FEED (gene)

Gene Symbol:

LGR5 Homo sapiens

Full name:

leucine rich repeat containing G protein-coupled receptor 5

Synonyms:

FEX, GPR49, GPR67, GRP49, HG38, leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, orphan G protein-coupled receptor HG38

Genomic Location:

Chr 12: 70120080-70264889

Description:

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal ...

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The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CREBP1CJUN_01 ,  CREB_Q4_01 ,  CREB_Q4 ,  TGAYRTCA_ATF3_Q6 ,  ATF_B ,  CREBP1_Q2 ,  GTGACGY_E4F1_Q6 ,  ATF_01 ,  WYAAANNRNNNGCG_UNKNOWN ,  CREB_02 ,  ATF3_Q6 ,  E4F1_Q6 ,  CTTTAAR_UNKNOWN ,  CREB_Q2 ,  TGACGTCA_ATF3_Q6 ,  CREB_Q2_01 ,  CREB_01

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Cytogenetic Map:

12q21.1

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