QuickView for Dcc;jsessionid=8880B1392CAE8AC35F65C7884BD672AA;jsessionid=AE4AADAA854BFE2E7B328963C6A8E766;jsessionid=4B15823FCBD5DE4020209ED8921420C4;jsessionid=D6D902C5306DA438F5B06C7E5A3556ED (gene)
- Gene Symbol:
- Dcc
Rattus norvegicus - Full name:
- DCC netrin 1 receptor
- Synonyms:
- netrin receptor DCC, colorectal tumor suppressor, deleted in colorectal carcinoma, putative colorectal tumor suppressor, tumor suppressor protein DCC
- Genomic Location:
- Chr 18: 68026795-69140741
- Description:
-
transmembrane protein of the immunoglobulin superfamily that plays dual roles as a receptor for the chemoattractant netrin-1 and possibly other signalling pathways, and as a gamma-secretase-dependent transcription coactivator
- Orthologs:
- Homo sapiens , Mus musculus , C. elegans , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
transmembrane signaling receptor activity | signaling receptor activity | identical protein binding | transcription coactivator activity | protein binding | transcription coregulator activity | netrin receptor activity
GO Biological Process
regulation of ERK1 and ERK2 cascade | cell morphogenesis | positive regulation of macromolecule biosynthetic process | positive regulation of cellular component organization | cell motility | regulation of neurogenesis | neuron projection morphogenesis | regulation of cell development | neuron migration | positive regulation of developmental process | cell differentiation | nervous system development | response to drug | cell part morphogenesis | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | central nervous system neuron axonogenesis | localization | cell projection morphogenesis | neuron development | central nervous system neuron differentiation | axon guidance | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | response to stimulus | cell morphogenesis involved in neuron differentiation | positive regulation of protein metabolic process | neuron projection guidance | programmed cell death | positive regulation of RNA biosynthetic process | regulation of nucleic acid-templated transcription | locomotion | response to nitrogen compound | central nervous system neuron development | apoptotic process | system development | regulation of signal transduction | central nervous system projection neuron axonogenesis | positive regulation of neuron projection development | multicellular organism development | cell migration | regulation of MAPK cascade | regulation of phosphorylation | anterior/posterior axon guidance | regulation of neuron differentiation | axon development | dorsal/ventral axon guidance | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | positive regulation of cell projection organization | positive regulation of intracellular signal transduction | axonogenesis | positive regulation of cell differentiation | regulation of cellular protein metabolic process | response to toxic substance | response to xenobiotic stimulus | cell morphogenesis involved in differentiation | spinal cord ventral commissure morphogenesis | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | transcription coactivator activity | regulation of RNA metabolic process | neuron differentiation | positive regulation of protein modification process | response to organic substance | regulation of intracellular signal transduction | anatomical structure development | response to amine | cell surface receptor signaling pathway | positive regulation of neurogenesis | cell projection organization | positive regulation of cell development | regulation of RNA biosynthetic process | neuron projection development | cell death | animal organ development | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | positive regulation of MAPK cascade | regulation of cell communication | signaling | cell development | positive regulation of phosphorylation | anatomical structure morphogenesis | regulation of nervous system development | regulation of developmental process | developmental process | netrin-activated signaling pathway | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | transcription coregulator activity | netrin receptor activity | central nervous system development | spinal cord development | positive regulation of metabolic process | positive regulation of neuron differentiation | response to amphetamine | regulation of cell projection organization | regulation of cell death | chemotaxis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | neuron projection | growth cone membrane | cell | distal axon | intrinsic component of membrane | membrane microdomain | cell projection | plasma membrane | membrane raft | site of polarized growth | cell periphery | axon | growth cone | membrane
