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QuickView for EPAC2;jsessionid=2AEED4CF800283478F4DE569FD3FA312;jsessionid=19130810637BF3B9855C1605D781E421 (gene)


Gene Symbol:
Rapgef4 Mus musculus Mus musculus
Full name:
Rap guanine nucleotide exchange factor (GEF) 4
Synonyms:
1300003D15Rik, 5730402K07Rik, 6330581N18Rik, EPAC 2, Epac-2, Epac2, mKIAA4040, rap guanine nucleotide exchange factor 4, cAMP-GEFII, cAMP-dependent Rap1 guanine-nucleotide exchange factor, cAMP-regulated guanine nucleotide exchange factor IIB, exchange factor directly activated by cAMP 2, exchange protein directly activated by cAMP 2
Genomic Location:
Chr 2: 71819344-72094433
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

guanyl-nucleotide exchange factor activity | GTPase binding | cyclic nucleotide binding | cAMP binding | enzyme binding | protein-containing complex binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | Ras GTPase binding | molecular function regulator | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | protein binding | Ras guanyl-nucleotide exchange factor activity | small GTPase binding | purine ribonucleotide binding | adenyl ribonucleotide binding | heterocyclic compound binding | small molecule binding

GO Biological Process

positive regulation of action potential | positive regulation of locomotion | guanyl-nucleotide exchange factor activity | exocytosis | regulation of transmission of nerve impulse | regulation of neurogenesis | intracellular signal transduction | regulation of cell development | regulation of localization | hormone secretion | establishment of localization | negative regulation of cellular process | cell differentiation | nervous system development | neurogenesis | positive regulation of cellular component movement | generation of neurons | positive regulation of protein secretion | positive regulation of neurological system process | cellular process | secretion | peptide hormone secretion | regulation of cell motility | localization | protein transport | negative regulation of signaling | macromolecule localization | regulation of neuron projection development | regulation of neurological system process | regulation of cell differentiation | regulation of cellular process | small GTPase mediated signal transduction | regulation of peptide secretion | response to stimulus | regulation of smooth muscle cell migration | secretion by cell | regulation of protein transport | regulation of peptide transport | modulation of chemical synaptic transmission | cell-cell signaling | insulin secretion | molecular function regulator | positive regulation of peptide secretion | regulation of membrane potential | system development | multicellular organism development | positive regulation of smooth muscle cell migration | regulation of hormone levels | regulation of neuron differentiation | positive regulation of secretion | organic substance transport | regulation of cell migration | peptide transport | vesicle-mediated transport | regulation of neuronal action potential | regulation of cellular component movement | second-messenger-mediated signaling | positive regulation of cell migration | regulated exocytosis | peptide secretion | cell communication | cyclic-nucleotide-mediated signaling | positive regulation of establishment of protein localization | regulation of locomotion | positive regulation of transport | regulation of establishment of protein localization | cAMP-mediated signaling | positive regulation of transmission of nerve impulse | regulation of exocytosis | anatomical structure development | amide transport | regulation of vesicle-mediated transport | calcium ion regulated exocytosis | Ras guanyl-nucleotide exchange factor activity | regulation of secretion | hormone transport | regulation of protein secretion | establishment of protein localization | positive regulation of protein transport | regulation of dendrite development | regulation of action potential | regulation of cell communication | signaling | protein localization | regulation of nervous system development | regulation of developmental process | developmental process | positive regulation of neuronal action potential | regulation of transport | signal release | negative regulation of synaptic transmission | regulation of cell projection organization | regulation of protein localization | protein secretion | positive regulation of cell motility | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

brush border | dendritic spine | non-motile cilium | dendrite | synapse | apical plasma membrane | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | distal axon | cytoplasm | dendritic tree | apical part of cell | presynapse | protein-containing complex | cell projection | neuron spine | postsynapse | plasma membrane | cilium | photoreceptor inner segment | photoreceptor outer segment | cone cell pedicle | site of polarized growth | 9+0 non-motile cilium | photoreceptor cell cilium | organelle | axon terminus | cell periphery | excitatory synapse | axon | basolateral plasma membrane | growth cone | neuron projection terminus | cytosol | intracellular | membrane