Correlation Engine 2.0
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QuickView for En1;jsessionid=B5FBE71D3A2BBFD37C3293A82B105CC1;jsessionid=7CCF00189DA60ABCD62C54AA27990B94;jsessionid=07AA7D721486D9384174596047265465;jsessionid=BAB2D430451DE72E9781A65983E3CFCD (gene)


Gene Symbol:
En1 Mus musculus Mus musculus
Full name:
engrailed 1
Synonyms:
En-1, Mo-en.1, engrailed-1, homeobox protein engrailed-1, homeobox protein en-1, mo-En-1
Genomic Location:
Chr 1: 122499258-122504548
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster Macaca mulatta Bos taurus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
AP4_01 ELK1_01 ELK1_02 CETS1P54_01 YY1_01 IRF1_01 HEN1_01 GATA3_01 MZF1_01 CEBPA_01
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_010133
Protein Names
P09065
Q3USA2
Q3USF7



GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

brain development | limb development | positive regulation of macromolecule biosynthetic process | regulation of programmed cell death | embryonic brain development | negative regulation of neuron death | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | neural tube patterning | social behavior | negative regulation of RNA biosynthetic process | embryonic appendage morphogenesis | cell differentiation | nervous system development | multicellular organism growth | neurogenesis | generation of neurons | pattern specification process | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | limb morphogenesis | developmental growth | neuron development | negative regulation of nucleic acid-templated transcription | learning | negative regulation of apoptotic process | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | drinking behavior | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | epithelium development | rostrocaudal neural tube patterning | head development | embryonic limb morphogenesis | metencephalon development | midbrain development | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | dorsal/ventral pattern formation | embryo development | anterior/posterior pattern specification | regulation of nucleic acid-templated transcription | negative regulation of neuron apoptotic process | system development | multicellular organism development | learning or memory | cerebellum development | regulation of gene expression | forelimb morphogenesis | nervous system process | positive regulation of cellular metabolic process | adult locomotory behavior | regulation of nitrogen compound metabolic process | embryonic forelimb morphogenesis | regulation of transcription by RNA polymerase II | pigmentation | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | cognition | locomotory behavior | neural tube development | hindbrain development | proximal/distal pattern formation | chordate embryonic development | regulation of cellular metabolic process | regulation of neuron apoptotic process | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | embryonic morphogenesis | motor learning | neuron differentiation | DNA-binding transcription factor activity | regionalization | anatomical structure development | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | embryonic organ development | behavior | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | dopaminergic neuron differentiation | adult behavior | feeding behavior | regulation of transcription, DNA-templated | cell development | anatomical structure morphogenesis | developmental process | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | central nervous system development | positive regulation of metabolic process | regulation of cell death | negative regulation of cell death | positive regulation of gene expression | multicellular organismal process | midbrain-hindbrain boundary development

GO Cellular Component

intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular | membrane