QuickView for FMO3;jsessionid=88EA2E330CD878CAC754C1C91B8FC32E;jsessionid=F1FD68221CD8937141DA1160EA850887;jsessionid=0F8F649C9C05E3F565D0CA4279CE6365;jsessionid=75C9799C560C5A83D378E7F30CCA7398 (gene)
- Gene Symbol:
- Fmo3
Rattus norvegicus - Full name:
- flavin containing monooxygenase 3
- Synonyms:
- dimethylaniline monooxygenase [N-oxide-forming] 3, FMO 3, dimethylaniline oxidase 3, hepatic flavin-containing monooxygenase 3, trimethylamine monooxygenase
- Genomic Location:
- Chr 13: 78658967-78678368
- Description:
-
responsible for methimazole S-oxidation and NADPH oxidation
- Orthologs:
- Homo sapiens , Mus musculus , C. elegans , Macaca mulatta , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
NADP binding | cofactor binding | carboxylic acid binding | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | anion binding | amino acid binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | trimethylamine monooxygenase activity | organic acid binding | heterocyclic compound binding | oxidoreductase activity | N,N-dimethylaniline monooxygenase activity | small molecule binding
GO Biological Process
cellular process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | drug metabolic process | trimethylamine monooxygenase activity | metabolic process | oxidation-reduction process | cellular metabolic process | oxidoreductase activity | N,N-dimethylaniline monooxygenase activity
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
