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QuickView for FOLR2;jsessionid=A6CBC83B23321811BB102D3C793F1B25;jsessionid=D5295C8A376D9C1E0B87143C51BC20C5 (gene)


Gene Symbol:
Folr2 Mus musculus Mus musculus
Full name:
folate receptor 2 (fetal)
Synonyms:
FBP2, FR-P3, FR-beta, Folbp-2, Folbp2, folate receptor beta, folate binding protein 2
Genomic Location:
Chr 7: 108988502-109012042
Description:
This gene encodes a receptor protein located on the plasma membrane that mediates folate uptake by cells. Mice lacking the product of this gene show no defects in embryonic development and grow normally into fertile adults. However, such mice were found to be highly susceptible to the teratogenic effects of arsenic. Alternate splicing of this gene ...
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Protein Names
Q05685



GO Molecular Function

modified amino acid binding | carboxylic acid binding | folic acid receptor activity | vitamin binding | anion binding | folic acid binding | amide binding | signaling receptor activity | ion binding | organic cyclic compound binding | drug binding | methotrexate binding | organic acid binding | heterocyclic compound binding | cargo receptor activity | small molecule binding

GO Biological Process

response to extracellular stimulus | response to nutrient levels | establishment of localization | protein targeting to ER | membrane fusion | cellular response to extracellular stimulus | response to drug | membrane organization | intracellular transport | posttranslational protein targeting to endoplasmic reticulum membrane | response to folic acid | cellular process | localization | protein transport | protein localization to endoplasmic reticulum | dicarboxylic acid transport | anion transport | macromolecule localization | establishment of localization in cell | folic acid transport | cell recognition | regulation of cellular process | cellular response to organonitrogen compound | folic acid receptor activity | cellular component organization | response to stimulus | intracellular protein transport | cellular response to vitamin | regulation of cell proliferation | sperm-egg recognition | reproduction | cellular localization | cellular response to organic cyclic compound | carboxylic acid transmembrane transport | folate transmembrane transport | response to nitrogen compound | cellular response to nutrient levels | reproductive process | cellular response to folic acid | vitamin transport | ion transmembrane transport | protein localization to membrane | organic substance transport | cell-cell recognition | vitamin transmembrane transport | peptide transport | vesicle-mediated transport | response to nutrient | organic acid transport | protein localization to organelle | fertilization | organic anion transport | cellular response to drug | cell communication | positive regulation of cell proliferation | single fertilization | establishment of protein localization to membrane | multicellular organism reproduction | cellular response to nutrient | response to organic substance | import into cell | anion transmembrane transport | establishment of protein localization to organelle | plasma membrane fusion | organic acid transmembrane transport | cofactor transport | fusion of sperm to egg plasma membrane involved in single fertilization | establishment of protein localization to endoplasmic reticulum | cellular protein localization | amide transport | endocytosis | cell adhesion | response to vitamin | folate import across plasma membrane | establishment of protein localization | drug transport | transmembrane transport | response to organic cyclic compound | protein localization | drug transmembrane transport | carboxylic acid transport | cellular macromolecule localization | protein targeting to membrane | receptor-mediated endocytosis | response to organonitrogen compound | protein targeting | ion transport | cargo receptor activity | cellular response to organic substance | sexual reproduction | multicellular organismal process

GO Cellular Component

intrinsic component of external side of plasma membrane | cell | intrinsic component of membrane | external side of plasma membrane | anchored component of plasma membrane | plasma membrane | anchored component of membrane | anchored component of external side of plasma membrane | cell periphery | cell surface | membrane | intrinsic component of plasma membrane