Correlation Engine 2.0
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QuickView for FPGS;jsessionid=6EADC2567EEF483DD36D21A40985240D;jsessionid=F61D9C0F1128976553A44CF511A9A161;jsessionid=F041865F78259928A48EDFEA536A9C2A (gene)


Gene Symbol:
Fpgs Rattus norvegicus Rattus norvegicus
Full name:
folylpolyglutamate synthase
Synonyms:
folylpolyglutamate synthase, mitochondrial
Genomic Location:
N/A
Description:
human homolog catalyzes an ATP-dependent ligation step in the synthesis of poly(gamma-glutamate) folate metabolites
Orthologs:
Homo sapiens Mus musculus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Protein Names
No proteins found.



GO Molecular Function

acid-amino acid ligase activity | catalytic activity | ligase activity, forming carbon-nitrogen bonds | tetrahydrofolylpolyglutamate synthase activity | ligase activity | dihydrofolate synthase activity

GO Biological Process

brain development | pteridine-containing compound biosynthetic process | nervous system development | cellular process | dicarboxylic acid metabolic process | folic acid-containing compound biosynthetic process | regeneration | cellular amino acid metabolic process | hepaticobiliary system development | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | folic acid-containing compound metabolic process | head development | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cofactor metabolic process | cellular biosynthetic process | pteridine-containing compound metabolic process | system development | nitrogen compound metabolic process | coenzyme biosynthetic process | multicellular organism development | tetrahydrofolylpolyglutamate synthase activity | glutamate metabolic process | cofactor biosynthetic process | liver development | dihydrofolate metabolic process | small molecule metabolic process | cellular amide metabolic process | cell proliferation | biosynthetic process | aromatic compound biosynthetic process | carboxylic acid metabolic process | gland development | tetrahydrofolylpolyglutamate biosynthetic process | anatomical structure development | metabolic process | organic substance metabolic process | animal organ development | amide biosynthetic process | organic acid metabolic process | developmental process | tetrahydrofolylpolyglutamate metabolic process | cellular modified amino acid metabolic process | heterocycle metabolic process | dihydrofolate synthase activity | central nervous system development | cellular metabolic process | dihydrofolate biosynthetic process | animal organ regeneration | multicellular organismal process

GO Cellular Component

mitochondrial matrix | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | membrane-enclosed lumen | cytosol | intracellular