QuickView for Fli-1;jsessionid=151134CBCE45DEFBCD0236A93F578AB4;jsessionid=DDB85B4EBE290C54DB3D839965E5F807;jsessionid=570467527D17E2579DB41DA5A12A6D51 (gene)

Gene Symbol:

Flii Mus musculus

Full name:

flightless I actin binding protein

Synonyms:

3632430F08Rik, Fliih, protein flightless-1 homolog, cytoskeletal actin-modulating protein, flightless I homolog

Genomic Location:

Chr 11: 60527651-60540723

Description:

This gene encodes a protein with gelsolin-like repeats and an N-terminal leucine-rich repeat domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. This protein may act as an actin-remodelling protein as well as a transcriptional coactivator. Homozygous knock...

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This gene encodes a protein with gelsolin-like repeats and an N-terminal leucine-rich repeat domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. This protein may act as an actin-remodelling protein as well as a transcriptional coactivator. Homozygous knockout mice show embryonic lethality. This protein may act to regulate wound repair. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SP1_Q6 ,  CTTTAAR_UNKNOWN ,  ALPHACP1_01 ,  SP1_Q6_01 ,  SP1_Q4_01 ,  CAGGTG_E12_Q6 ,  GGGCGGR_SP1_Q6

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