QuickView for G6PD;jsessionid=6B1CB9DA46C78D51C4D1100F27D4706B;jsessionid=424892298015191030C2F7F1BA2A33C2 (gene)
- Gene Symbol:
- G6pd
Rattus norvegicus - Full name:
- glucose-6-phosphate dehydrogenase
- Synonyms:
- G6pdx, glucose-6-phosphate 1-dehydrogenase, glucose-6-phosphate dehydrogenase X-linked
- Genomic Location:
- Chr X: 160186451-160192313
- Description:
-
catalyzes the first rate-limiting step in the pentose phosphate pathway; may mediate peroxynitrite functions in neuroprotection against nitric oxide-mediated apoptosis
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Canis lupus familiaris , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
oxidoreductase activity, acting on CH-OH group of donors | NADP binding | cofactor binding | nucleotide binding | coenzyme binding | monosaccharide binding | catalytic activity | glucose binding | identical protein binding | organic cyclic compound binding | carbohydrate binding | protein binding | protein homodimerization activity | protein dimerization activity | glucose-6-phosphate dehydrogenase activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
NADP biosynthetic process | response to extracellular stimulus | regulation of blood vessel diameter | regulation of muscle system process | response to nutrient levels | regulation of systemic arterial blood pressure by hormone | oxidoreductase activity, acting on CH-OH group of donors | regulation of cell development | regulation of localization | sulfur compound metabolic process | regulation of programmed cell death | regulation of cardiac muscle cell differentiation | erythrocyte homeostasis | glutathione metabolic process | myeloid cell differentiation | negative regulation of cellular process | response to metal ion | glucose metabolic process | regulation of heart growth | cell differentiation | angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure | negative regulation of organ growth | nicotinamide nucleotide biosynthetic process | response to drug | erythrocyte maturation | response to antibiotic | regulation of neuron death | sterol metabolic process | cellular process | negative regulation of muscle organ development | cell maturation | nucleotide metabolic process | regulation of cell growth involved in cardiac muscle cell development | negative regulation of developmental growth | immune system development | ribose phosphate metabolic process | regulation of striated muscle tissue development | regulation of multicellular organism growth | myeloid cell development | response to inorganic substance | negative regulation of cellular metabolic process | regulation of cell differentiation | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | negative regulation of muscle hypertrophy | regulation of cellular process | negative regulation of cardiocyte differentiation | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | steroid biosynthetic process | angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure | regulation of systemic arterial blood pressure mediated by a chemical signal | negative regulation of cardiac muscle tissue development | response to stimulus | positive regulation of blood pressure | pentose-phosphate shunt | negative regulation of striated muscle cell differentiation | regulation of blood vessel size | response to stress | positive regulation of cation transmembrane transport | cellular nitrogen compound biosynthetic process | alcohol metabolic process | response to alcohol | cellular nitrogen compound metabolic process | pentose biosynthetic process | negative regulation of muscle tissue development | carbohydrate derivative biosynthetic process | blood circulation | negative regulation of metabolic process | cofactor metabolic process | hemopoiesis | cellular biosynthetic process | response to iron ion | nucleotide biosynthetic process | negative regulation of blood pressure | myeloid cell homeostasis | response to ethanol | negative regulation of blood vessel diameter | organic hydroxy compound metabolic process | system development | nitrogen compound metabolic process | negative regulation of growth | coenzyme biosynthetic process | positive regulation of calcium ion transmembrane transport | multicellular organism development | phosphorus metabolic process | interleukin-12 production | lipid metabolic process | cellular response to oxidative stress | cellular response to stress | regulation of blood pressure | negative regulation of cardiac muscle cell differentiation | regulation of systemic arterial blood pressure by renin-angiotensin | organophosphate metabolic process | regulation of systemic arterial blood pressure | sterol biosynthetic process | cofactor biosynthetic process | negative regulation of cardiac muscle hypertrophy | positive regulation of ion transmembrane transport | regulation of nitrogen compound metabolic process | monosaccharide metabolic process | small molecule metabolic process | cellular amide metabolic process | response to oxidative stress | nucleobase-containing small molecule metabolic process | homeostasis of number of cells | carbohydrate biosynthetic process | biosynthetic process | cholesterol biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | vasoconstriction | lipid biosynthetic process | carbohydrate metabolic process | regulation of calcium ion transmembrane transport | negative regulation of protein glutathionylation | response to toxic substance | interleukin-10 production | erythrocyte development | phosphate-containing compound metabolic process | endocrine process | regulation of cellular metabolic process | regulation of neuron apoptotic process | glyceraldehyde-3-phosphate metabolic process | regulation of protein metabolic process | negative regulation of striated muscle tissue development | homeostatic process | peptide metabolic process | pentose-phosphate shunt, oxidative branch | regulation of tube size | positive regulation of transport | negative regulation of cell growth | positive regulation of systemic arterial blood pressure | cellular aldehyde metabolic process | cytokine production | pyridine nucleotide biosynthetic process | regulation of cardiac muscle hypertrophy | regulation of growth | response to organic substance | regulation of cardiac muscle tissue development | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | anatomical structure development | vasodilation | metabolic process | hexose metabolic process | developmental maturation | cholesterol metabolic process | oxidation-reduction process | regulation of tube diameter | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | positive regulation of ion transport | negative regulation of cellular protein metabolic process | glucose 6-phosphate metabolic process | NADPH regeneration | regulation of striated muscle cell differentiation | regulation of ion transmembrane transport | renal system process | response to iron(III) ion | negative regulation of protein metabolic process | steroid metabolic process | negative regulation of cell growth involved in cardiac muscle cell development | glucose-6-phosphate dehydrogenase activity | response to organic cyclic compound | ribose phosphate biosynthetic process | negative regulation of systemic arterial blood pressure | cell development | regulation of developmental growth | NADP metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | regulation of organ growth | regulation of developmental process | regulation of ion transport | renal system process involved in regulation of systemic arterial blood pressure | developmental process | regulation of muscle cell differentiation | erythrocyte differentiation | nicotinamide nucleotide metabolic process | regulation of cell growth | regulation of calcium ion transport | carbohydrate derivative metabolic process | regulation of transport | regulation of reactive oxygen species metabolic process | cellular modified amino acid metabolic process | heterocycle metabolic process | negative regulation of muscle cell differentiation | pentose metabolic process | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | regulation of cell death | oxidoreductase activity | regulation of blood vessel diameter by renin-angiotensin | response to food | negative regulation of cell development | positive regulation of blood vessel diameter | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of calcium ion transport | negative regulation of reactive oxygen species metabolic process | regulation of muscle organ development | multicellular organismal process
GO Cellular Component
cytoplasmic side of plasma membrane | intracellular membrane-bounded organelle | cell | cytoplasmic side of membrane | cytoplasm | intracellular organelle | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | cytosol | intracellular | membrane
