QuickView for GAB3;jsessionid=7297FCA07ED26C51EF4D3C7F5E59DDF2;jsessionid=6AA64575065D9DA475D5AFE9D61A9009;jsessionid=3D8C4D53AFFC1B1C7DD79EB347D1445C;jsessionid=50C570DEECB9EEC54202493F3D89F354 (gene)

Gene Symbol:

GAB3 Homo sapiens

Full name:

GRB2 associated binding protein 3

Synonyms:

GRB2-associated-binding protein 3, DOS/Gab family member 3, GRB2-associated binder 3, Gab3 scaffolding protein, growth factor receptor bound protein 2-associated protein 3

Genomic Location:

Chr X: 153556720-153632542

Description:

This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates...

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This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Cytogenetic Map:

Xq28

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