QuickView for GAB3;jsessionid=E79B83B60508FBB8C65D7F5339C66F91;jsessionid=E31DFDFD5C586EE5EE469C1CD5582E16;jsessionid=81DEACE33B2B7A181D4BD340B56F71DA;jsessionid=F8EC2F9B4929ECDB0BF9E8C1EF0A9286;jsessionid=208E9AAC7060D7B98461715C996A9619;jsessionid=327AB1E1FA91567C72038A315CB4CACD;jsessionid=89F6000097640663338FA1D5BCA54A80;jsessionid=DB2FEB023EAA1B2BADD2FFC89E0EE426 (gene)

Gene Symbol:

GAB3 Homo sapiens

Full name:

GRB2 associated binding protein 3

Synonyms:

GRB2-associated-binding protein 3, DOS/Gab family member 3, GRB2-associated binder 3, Gab3 scaffolding protein, growth factor receptor bound protein 2-associated protein 3

Genomic Location:

Chr X: 153556720-153632542

Description:

This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates...

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This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Cytogenetic Map:

Xq28

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