QuickView for GADD45A;jsessionid=A0DC8F91F4808905D06C50C8A3DC55A5;jsessionid=6E3C74EE05F7CB69891A020D8F5A21E8 (gene)
- Gene Symbol:
- Gadd45a
Rattus norvegicus - Full name:
- growth arrest and DNA-damage-inducible, alpha
- Synonyms:
- Ddit1, Gadd45, growth arrest and DNA damage-inducible protein GADD45 alpha, DDIT-1, DNA damage-inducible transcript 1 protein, DNA-damage-inducible transcript 1, growth arrest and DNA-damage-inducible 45 alpha
- Genomic Location:
- Chr 4: 96649941-96652243
- Description:
-
may mediate a delay in G2 to M cell cycle progression; may induce DNA repair
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Pan troglodytes , Bos taurus , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
NFE2_01 , GATA1_01 , AP1_Q2 , AP1_Q6 , AP1_C , CATRRAGC_UNKNOWN , GFI1_01 , AREB6_02 , BACH2_01 , CTGRYYYNATT_UNKNOWN
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
sequence-specific DNA binding | kinase binding | transcription regulatory region DNA binding | core promoter binding | enzyme binding | nucleic acid binding | protein N-terminus binding | RNA polymerase II core promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | identical protein binding | protein heterodimerization activity | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | double-stranded DNA binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | core promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
negative regulation of phosphorylation | response to radiation | intracellular signal transduction | positive regulation of apoptotic process | regulation of programmed cell death | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | microtubule cytoskeleton organization | negative regulation of protein phosphorylation | positive regulation of phosphate metabolic process | microtubule-based process | cellular process | positive regulation of reactive oxygen species metabolic process | positive regulation of protein kinase activity | microtubule organizing center organization | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | positive regulation of cellular protein metabolic process | cellular component organization | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | cellular response to mechanical stimulus | positive regulation of protein metabolic process | response to stress | negative regulation of protein kinase activity | activation of MAPKKK activity | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | activation of protein kinase activity | regulation of cellular response to stress | regulation of signal transduction | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of MAPK cascade | cellular response to DNA damage stimulus | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | signal transduction in response to DNA damage | cellular response to stress | cell cycle | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular response to radiation | positive regulation of p38MAPK cascade | regulation of nitrogen compound metabolic process | positive regulation of JNK cascade | positive regulation of intracellular signal transduction | regulation of cellular protein metabolic process | G2/M transition of mitotic cell cycle | mitotic cell cycle phase transition | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | positive regulation of signal transduction | cell cycle G2/M phase transition | regulation of protein phosphorylation | regulation of mitotic cell cycle | positive regulation of molecular function | positive regulation of protein modification process | centrosome cycle | cell cycle arrest | regulation of kinase activity | response to mechanical stimulus | regulation of intracellular signal transduction | mitotic cell cycle | negative regulation of mitotic cell cycle | positive regulation of cell death | negative regulation of cellular protein metabolic process | positive regulation of programmed cell death | positive regulation of kinase activity | cellular response to ionizing radiation | regulation of phosphate metabolic process | cytoskeleton organization | regulation of JNK cascade | positive regulation of MAPK cascade | negative regulation of cell cycle | negative regulation of protein metabolic process | regulation of stress-activated MAPK cascade | regulation of cell communication | negative regulation of molecular function | signaling | mitotic cell cycle arrest | positive regulation of phosphorylation | positive regulation of MAP kinase activity | organelle organization | regulation of reactive oxygen species metabolic process | cell cycle phase transition | positive regulation of metabolic process | regulation of cell death | response to ionizing radiation | positive regulation of signaling | signal transduction | regulation of signaling | regulation of p38MAPK cascade | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | nucleoplasm | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
