QuickView for GAPDH;jsessionid=AC9E6D3DE573E5B6C97F23155DE57D97;jsessionid=B9B09DD55562466BE0A1CD022A211592 (gene)
- Gene Symbol:
- Gapdh
Mus musculus - Full name:
- glyceraldehyde-3-phosphate dehydrogenase
- Synonyms:
- Gapd, glyceraldehyde-3-phosphate dehydrogenase, peptidyl-cysteine S-nitrosylase GAPDH
- Genomic Location:
- Chr 6: 125111870-125115601
- Description:
-
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein was originally identified as a key glycolytic enzyme that converts D-glyceraldehyde 3-phosphate (G3P) int...
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
aspartic-type endopeptidase inhibitor activity | endopeptidase inhibitor activity | peptidyl-cysteine S-nitrosylase activity | enzyme binding | disordered domain specific binding | enzyme inhibitor activity | molecular function regulator | catalytic activity | protein domain specific binding | cytoskeletal protein binding | identical protein binding | protein binding | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | transferase activity | microtubule binding | tubulin binding | peptidase inhibitor activity | enzyme regulator activity | oxidoreductase activity
GO Biological Process
positive regulation of cell killing | purine ribonucleotide metabolic process | purine ribonucleoside monophosphate biosynthetic process | aspartic-type endopeptidase inhibitor activity | endopeptidase inhibitor activity | response to cytokine | nucleoside phosphate catabolic process | positive regulation of apoptotic process | protein stabilization | glycolytic process | regulation of localization | regulation of programmed cell death | peptidyl-amino acid modification | defense response to other organism | neuron death | negative regulation of cellular process | glucose metabolic process | microtubule cytoskeleton organization | defense response | nicotinamide nucleotide biosynthetic process | generation of precursor metabolites and energy | organophosphate catabolic process | killing by host of symbiont cells | positive regulation of protein secretion | microtubule-based process | negative regulation of proteolysis | interaction with symbiont | cellular process | organic substance catabolic process | peptidyl-cysteine S-nitrosylase activity | nucleotide metabolic process | positive regulation of killing of cells of other organism | ribose phosphate metabolic process | purine nucleotide biosynthetic process | regulation of proteolysis | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | carbohydrate catabolic process | negative regulation of cellular metabolic process | interspecies interaction between organisms | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | cellular response to interferon-gamma | regulation of peptide secretion | response to stimulus | enzyme inhibitor activity | defense response to fungus | purine nucleotide metabolic process | monocarboxylic acid metabolic process | response to stress | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | programmed cell death | positive regulation of cytokine secretion | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | regulation of protein transport | negative regulation of metabolic process | cofactor metabolic process | protein modification process | regulation of peptide transport | cellular biosynthetic process | macromolecule modification | nucleobase-containing compound catabolic process | molecular function regulator | nucleotide biosynthetic process | positive regulation of peptide secretion | response to nitrogen compound | apoptotic process | response to external biotic stimulus | ATP biosynthetic process | nitrogen compound metabolic process | regulation of protein stability | coenzyme biosynthetic process | multicellular organism development | negative regulation of catalytic activity | regulation of peptidase activity | phosphorus metabolic process | ribonucleoside monophosphate biosynthetic process | regulation of catalytic activity | regulation of killing of cells of other organism | positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction | negative regulation of peptidase activity | regulation of gene expression | cell killing | positive regulation of secretion | organophosphate metabolic process | modification of morphology or physiology of other organism | hexose biosynthetic process | nucleotide phosphorylation | cofactor biosynthetic process | response to ammonium ion | regulation of nitrogen compound metabolic process | monosaccharide metabolic process | neuron apoptotic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | carbohydrate biosynthetic process | cellular response to cytokine stimulus | biosynthetic process | pyruvate metabolic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | phosphorylation | purine ribonucleotide biosynthetic process | carbohydrate metabolic process | nucleotide catabolic process | nucleoside triphosphate biosynthetic process | phosphate-containing compound metabolic process | response to fungus | regulation of cellular metabolic process | antimicrobial humoral immune response mediated by antimicrobial peptide | humoral immune response | regulation of protein metabolic process | aromatic compound catabolic process | positive regulation of establishment of protein localization | positive regulation of transport | drug metabolic process | carboxylic acid metabolic process | disruption by host of symbiont cells | regulation of cytokine secretion | pyridine nucleotide biosynthetic process | antimicrobial humoral response | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | protein metabolic process | regulation of establishment of protein localization | response to organic substance | nucleoside diphosphate metabolic process | killing of cells of other organism | peptidyl-cysteine S-nitrosylation | anatomical structure development | metabolic process | hexose metabolic process | oxidation-reduction process | regulation of secretion | positive regulation of cell death | gluconeogenesis | immune response | nucleobase-containing compound metabolic process | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | organic substance metabolic process | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | regulation of protein secretion | positive regulation of programmed cell death | protein nitrosylation | ATP generation from ADP | cytoskeleton organization | negative regulation of translation | response to interferon-gamma | positive regulation of cytokine production | pyruvate biosynthetic process | positive regulation of protein transport | peptidyl-cysteine S-trans-nitrosylation | negative regulation of protein metabolic process | ADP metabolic process | negative regulation of molecular function | ribose phosphate biosynthetic process | organic acid metabolic process | peptidase inhibitor activity | cellular protein metabolic process | enzyme regulator activity | regulation of cytokine production | regulation of endopeptidase activity | response to biotic stimulus | developmental process | organelle organization | nicotinamide nucleotide metabolic process | cellular protein modification process | carbohydrate derivative metabolic process | regulation of transport | innate immune response | heterocycle metabolic process | negative regulation of hydrolase activity | immune system process | cellular metabolic process | ATP metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | oxidoreductase activity | regulation of translation | nucleoside diphosphate phosphorylation | response to other organism | nucleoside monophosphate biosynthetic process | negative regulation of endopeptidase activity | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
GAIT complex | intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | cell | cytoplasm | intracellular organelle | protein-containing complex | endomembrane system | plasma membrane | nuclear envelope | ribonucleoprotein complex | lipid droplet | microtubule cytoskeleton | mitochondrion | membrane-bounded organelle | nucleus | organelle | cell periphery | cytosol | cytoskeleton | intracellular | myelin sheath | membrane
