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QuickView for GBA;jsessionid=D4DF8A9908C8E05C0CAB1E9C282FF909;jsessionid=111807960AF7B007B6BDA902173F5B9C (gene)


Gene Symbol:
GBA Bos taurus Bos taurus
Full name:
glucosidase, beta; acid (includes glucosylceramidase)
Synonyms:
MGC137522
Genomic Location:
Chr 3: 16784027-16788846
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus C. elegans Pan troglodytes Danio rerio Canis lupus familiaris Gallus gallus
External Links:
Entrez Gene


Transcripts Names
NM_001046421
Protein Names
Q2KHZ8



GO Molecular Function

signaling receptor binding | hydrolase activity | hydrolase activity, hydrolyzing O-glycosyl compounds | catalytic activity | hydrolase activity, acting on glycosyl bonds | scavenger receptor binding | glucosylceramidase activity | protein binding

GO Biological Process

response to extracellular stimulus | negative regulation of phosphorylation | positive regulation of action potential | positive regulation of macromolecule biosynthetic process | regulation of dephosphorylation | response to nutrient levels | negative regulation of MAPK cascade | regulation of transmission of nerve impulse | response to cytokine | positive regulation of cellular component organization | glycosphingolipid metabolic process | macroautophagy | negative regulation of protein homooligomerization | regulation of autophagy | negative regulation of neuron death | glycolipid catabolic process | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | cellular response to tumor necrosis factor | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | cellular response to extracellular stimulus | positive regulation of protein catabolic process | negative regulation of protein phosphorylation | polyol metabolic process | positive regulation of phosphate metabolic process | regulation of protein oligomerization | regulation of organelle organization | regulation of neuron death | positive regulation of dephosphorylation | positive regulation of neurological system process | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | negative regulation of signaling | carbohydrate derivative catabolic process | positive regulation of lipoprotein metabolic process | sphingolipid metabolic process | cellular response to starvation | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of neurological system process | regulation of cellular process | regulation of metabolic process | catabolic process | regulation of protein complex assembly | positive regulation of protein complex disassembly | positive regulation of cellular protein metabolic process | ceramide catabolic process | cellular component organization | cellular lipid metabolic process | positive regulation of autophagy of mitochondrion | positive regulation of cellular protein catabolic process | response to stimulus | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | response to stress | negative regulation of protein kinase activity | cellular nitrogen compound biosynthetic process | alcohol metabolic process | ceramide metabolic process | glucosylceramide metabolic process | response to starvation | positive regulation of proteolysis involved in cellular protein catabolic process | sphingolipid biosynthetic process | positive regulation of proteolysis | negative regulation of protein oligomerization | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | positive regulation of protein dephosphorylation | positive regulation of mitochondrion organization | regulation of membrane potential | organic hydroxy compound metabolic process | cellular response to nutrient levels | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | autophagosome organization | negative regulation of phosphate metabolic process | negative regulation of interleukin-6 production | negative regulation of catalytic activity | regulation of MAPK cascade | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of phosphorylation | regulation of protein complex disassembly | cellular response to stress | negative regulation of cytokine production | positive regulation of cellular metabolic process | positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization | regulation of nitrogen compound metabolic process | small molecule metabolic process | negative regulation of protein serine/threonine kinase activity | glycosphingolipid catabolic process | cellular amide metabolic process | regulation of neuronal action potential | glycolipid metabolic process | cellular response to cytokine stimulus | biosynthetic process | diol biosynthetic process | regulation of cellular protein metabolic process | positive regulation of proteasomal protein catabolic process | lipid biosynthetic process | glycosylceramide metabolic process | membrane lipid catabolic process | positive regulation of protein lipidation | vacuole organization | autophagy | regulation of mitochondrion organization | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | cellular lipid catabolic process | regulation of protein metabolic process | regulation of protein phosphorylation | negative regulation of MAP kinase activity | regulation of autophagy of mitochondrion | regulation of proteasomal ubiquitin-dependent protein catabolic process | regulation of protein homooligomerization | positive regulation of protein modification process | response to organic substance | sphingosine biosynthetic process | sphingosine metabolic process | positive regulation of transmission of nerve impulse | sphingoid biosynthetic process | regulation of protein dephosphorylation | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | metabolic process | membrane lipid metabolic process | positive regulation of ubiquitin-dependent protein catabolic process | regulation of protein catabolic process | regulation of proteasomal protein catabolic process | lipid catabolic process | negative regulation of protein complex assembly | organic substance metabolic process | negative regulation of cellular protein metabolic process | amide biosynthetic process | glucosylceramide catabolic process | regulation of phosphate metabolic process | positive regulation of autophagy | negative regulation of protein metabolic process | regulation of action potential | organonitrogen compound catabolic process | regulation of cell communication | response to mitochondrial depolarisation | negative regulation of molecular function | negative regulation of signal transduction | regulation of cytokine production | organelle organization | positive regulation of neuronal action potential | carbohydrate derivative metabolic process | sphingolipid catabolic process | positive regulation of metabolic process | regulation of lipoprotein metabolic process | cellular metabolic process | response to tumor necrosis factor | cellular response to organic substance | regulation of cell death | ceramide biosynthetic process | negative regulation of cell death | regulation of interleukin-6 production | regulation of ubiquitin-dependent protein catabolic process | termination of signal transduction | regulation of cellular component organization | positive regulation of signaling | regulation of signaling | glycosylceramide catabolic process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cell | vacuolar lumen | cytoplasm | intracellular organelle | vacuole | lytic vacuole | extracellular region | membrane-bounded organelle | organelle | lysosome | extracellular space | membrane-enclosed lumen | lysosomal lumen | intracellular | lysosomal membrane | membrane | vacuolar membrane