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QuickView for GCAP1;jsessionid=7775EDE0A84FA8E341E67ADB1229FCF0;jsessionid=4B282A7D9F6EDFD0E72A20723946298C (gene)


Gene Symbol:
Guca1a Mus musculus Mus musculus
Full name:
guanylate cyclase activator 1a (retina)
Synonyms:
GC-A, Gcap1, Guca1, mGCAP1, guanylyl cyclase-activating protein 1, GCAP 1
Genomic Location:
Chr 17: 47531507-47537533
Description:
This gene encodes a calcium-binding photoreceptor protein. The encoded protein may be involved in modulation of guanylyl cyclase activity, and in turn, the mammalian cone phototransduction cascade. Disruption of this gene results in the retinal degeneration associated with cone dystrophy.
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_008189
XR_001782041
XM_011246296
Protein Names
P43081
Q8R0H3



GO Molecular Function

enzyme activator activity | cation binding | molecular function regulator | ion binding | guanylate cyclase regulator activity | guanylate cyclase activator activity | calcium ion binding | enzyme regulator activity | calcium sensitive guanylate cyclase activator activity | metal ion binding

GO Biological Process

positive regulation of cyclase activity | response to radiation | detection of stimulus | positive regulation of lyase activity | enzyme activator activity | positive regulation of phosphate metabolic process | detection of light stimulus | positive regulation of cellular biosynthetic process | cellular process | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | response to stimulus | regulation of guanylate cyclase activity | molecular function regulator | phototransduction | detection of abiotic stimulus | response to light stimulus | positive regulation of guanylate cyclase activity | regulation of catalytic activity | nervous system process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of cyclase activity | guanylate cyclase regulator activity | cell communication | regulation of cellular metabolic process | positive regulation of molecular function | visual perception | sensory perception of light stimulus | guanylate cyclase activator activity | regulation of phosphate metabolic process | sensory perception | signaling | enzyme regulator activity | calcium sensitive guanylate cyclase activator activity | positive regulation of metabolic process | signal transduction | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

non-motile cilium | neuron projection | cell | cell projection | cilium | photoreceptor inner segment | photoreceptor outer segment | 9+0 non-motile cilium | photoreceptor cell cilium | organelle | membrane