QuickView for GCG;jsessionid=848D67918D1FDCDB75DE821ECDCFC68F;jsessionid=5456B3639BBA539229D20EFD005C4C22;jsessionid=C3EB41C2EF6293D1F13792D15730461D (gene)
- Gene Symbol:
- Gcg
Mus musculus - Full name:
- glucagon
- Synonyms:
- GLP-1, Glu, PPG, glucagon, glucagon-like peptide I
- Genomic Location:
- Chr 2: 62312587-62321710
- Description:
-
This gene encodes glucagon, a pancreatic hormone that counteracts the action of insulin in the bloodstream. The encoded protein is processed to generate glucagon and two other glucagon-like peptides, GLP1 and GLP2. Glucagon stimulates gluconeogenesis, glycogenolysis and lipolysis. GLP1 induces secretion of insulin, suppresses glucagon secretion and...
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AACTTT_UNKNOWN , EVI1_02 , CHOP_01 , FREAC3_01 , TBP_01 , CDX2_Q5 , TGCTTTG_MIR330 , CTTTGCA_MIR527 , CAGGTA_AREB6_01 , CAGGTG_E12_Q6
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
signaling receptor binding | hormone activity | molecular function regulator | glucagon receptor binding | protein binding | receptor regulator activity | G-protein coupled receptor binding | receptor ligand activity
GO Biological Process
response to extracellular stimulus | regulation of ERK1 and ERK2 cascade | regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter | positive regulation of insulin secretion involved in cellular response to glucose stimulus | negative regulation of execution phase of apoptosis | positive regulation of macromolecule biosynthetic process | response to nutrient levels | positive regulation of cellular component organization | regulation of cellular localization | intracellular signal transduction | regulation of localization | regulation of carbohydrate metabolic process | regulation of programmed cell death | positive regulation of peptidyl-threonine phosphorylation | negative regulation of cellular process | protein kinase A signaling | regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter | positive regulation of phosphate metabolic process | regulation of organelle organization | regulation of peptide hormone secretion | positive regulation of protein secretion | positive regulation of cellular biosynthetic process | cellular process | positive regulation of peptidyl-serine phosphorylation | positive regulation of protein kinase activity | regulation of histone modification | negative regulation of apoptotic process | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of appetite | regulation of binding | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | negative regulation of appetite | positive regulation of protein binding | regulation of peptide secretion | regulation of histone methylation | response to stimulus | regulation of insulin secretion | positive regulation of protein metabolic process | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter | positive regulation of hormone secretion | hormone activity | regulation of protein transport | G-protein coupled receptor signaling pathway | positive regulation of RNA biosynthetic process | regulation of peptide transport | molecular function regulator | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | regulation of signal transduction | positive regulation of organelle organization | regulation of MAPK cascade | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of catalytic activity | regulation of insulin secretion involved in cellular response to glucose stimulus | regulation of phosphorylation | positive regulation of gluconeogenesis | regulation of hormone levels | regulation of hormone secretion | positive regulation of chromosome organization | positive regulation of calcium ion import | regulation of gene expression | positive regulation of secretion | regulation of response to food | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | second-messenger-mediated signaling | regulation of cellular protein metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of histone H3-K4 methylation | cyclic-nucleotide-mediated signaling | regulation of protein metabolic process | positive regulation of signal transduction | regulation of histone H3-K4 methylation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of transport | positive regulation of peptide hormone secretion | positive regulation of molecular function | regulation of signaling receptor activity | receptor regulator activity | regulation of establishment of protein localization | negative regulation of response to food | positive regulation of protein modification process | positive regulation of insulin secretion | cAMP-mediated signaling | regulation of kinase activity | regulation of intracellular signal transduction | regulation of glucose metabolic process | positive regulation of glucose metabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | regulation of secretion | receptor ligand activity | positive regulation of ion transport | positive regulation of histone modification | regulation of protein secretion | positive regulation of ERK1 and ERK2 cascade | positive regulation of kinase activity | regulation of phosphate metabolic process | regulation of chromosome organization | positive regulation of binding | positive regulation of MAPK cascade | positive regulation of protein transport | regulation of peptidyl-serine phosphorylation | positive regulation of carbohydrate metabolic process | regulation of calcium ion import | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | signaling | regulation of transcription, DNA-templated | regulation of protein binding | positive regulation of phosphorylation | regulation of ion transport | regulation of calcium ion transport | regulation of transport | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | regulation of gluconeogenesis | positive regulation of metabolic process | regulation of execution phase of apoptosis | positive regulation of histone methylation | regulation of protein localization | regulation of cell death | negative regulation of cell death | regulation of cellular component organization | positive regulation of calcium ion transport | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | regulation of chromatin organization | regulation of phosphorus metabolic process
GO Cellular Component
cell | cytoplasm | extracellular region | extracellular space | intracellular
