QuickView for GCLC;jsessionid=9458CF7126141EC75D74CCC3AA559853;jsessionid=05E518344DFA35649C18F5205724B6F1 (gene)
- Gene Symbol:
- gclc
Danio rerio - Full name:
- glutamate-cysteine ligase, catalytic subunit
- Synonyms:
- cb1049, fe36e11, wu:fe36e11
- Genomic Location:
- Chr 13: 1595064-1630065
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
ADP binding | cofactor binding | glutamate-cysteine ligase activity | cation binding | magnesium ion binding | carboxylic acid binding | ribonucleotide binding | nucleotide binding | coenzyme binding | carbohydrate derivative binding | acid-amino acid ligase activity | catalytic activity | ligase activity, forming carbon-nitrogen bonds | anion binding | adenyl nucleotide binding | amino acid binding | purine nucleotide binding | ion binding | organic cyclic compound binding | ligase activity | glutamate binding | purine ribonucleotide binding | adenyl ribonucleotide binding | organic acid binding | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
sulfur compound metabolic process | regulation of programmed cell death | glutathione metabolic process | response to hormone | negative regulation of cellular process | negative regulation of RNA biosynthetic process | cellular process | cellular homeostasis | dicarboxylic acid metabolic process | serine family amino acid metabolic process | negative regulation of nucleic acid-templated transcription | negative regulation of apoptotic process | negative regulation of cellular metabolic process | cellular amino acid metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | response to stimulus | peptide biosynthetic process | regulation of blood vessel size | response to stress | cell redox homeostasis | cellular nitrogen compound biosynthetic process | response to temperature stimulus | cellular nitrogen compound metabolic process | blood circulation | negative regulation of metabolic process | cofactor metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | sulfur amino acid metabolic process | nitrogen compound metabolic process | regulation of gene expression | glutamate metabolic process | cofactor biosynthetic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | cellular amide metabolic process | response to oxidative stress | biosynthetic process | regulation of cellular metabolic process | homeostatic process | peptide metabolic process | regulation of RNA metabolic process | regulation of tube size | carboxylic acid metabolic process | response to organic substance | glutathione biosynthetic process | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | amide biosynthetic process | response to heat | regulation of transcription, DNA-templated | organic acid metabolic process | cysteine metabolic process | cellular modified amino acid metabolic process | cellular metabolic process | regulation of cell death | negative regulation of cell death | multicellular organismal process
GO Cellular Component
catalytic complex | cell | cytoplasm | protein-containing complex | glutamate-cysteine ligase complex | intracellular
