QuickView for GRIK1;jsessionid=151B1033823F1B89C7F6AA0DAC006D05;jsessionid=9EF2FAFB5019D5CCE2D7CA9078D8A2A9 (gene)

Gene Symbol:

Grik1 Rattus norvegicus

Full name:

glutamate ionotropic receptor kainate type subunit 1

Synonyms:

GluK1, GluR5, glutamate receptor ionotropic, kainate 1, glutamate receptor 5

Genomic Location:

Chr 11: 27703875-28106450

Description:

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by th...

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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene.

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Orthologs:

Homo sapiens ,  Mus musculus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AACTTT_UNKNOWN ,  MEF2_01 ,  HSF1_01 ,  HSF2_01 ,  OLF1_01 ,  PAX4_01 ,  MMEF2_Q6 ,  E2F1_Q4 ,  MAZR_01 ,  STAT1_03 ,  DBP_Q6 ,  TCF1P_Q6 ,  HMGIY_Q6 ,  TAATAAT_MIR126 ,  TGTTTGY_HNF3_Q6 ,  RGAANNTTC_HSF1_01 ,  YTATTTTNR_MEF2_02 ,  TGACAGNY_MEIS1_01 ,  CCCNNGGGAR_OLF1_01 ,  GGGTGGRR_PAX4_03 ,  GGGCGGR_SP1_Q6

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