QuickView for GRIN2B;jsessionid=C12A10A58E3870B513588554607B125B;jsessionid=05C48472CCD5D8BF6CE983C27DF3284A (gene)
- Gene Symbol:
- Grin2b
Mus musculus - Full name:
- glutamate receptor, ionotropic, NMDA2B (epsilon 2)
- Synonyms:
- AW490526, GluN2B, NR2B, Nmdar2b, glutamate receptor ionotropic, NMDA 2B, GluRepsilon2, N-methyl D-aspartate receptor 2B, N-methyl D-aspartate receptor subtype 2B, glutamate [NMDA] receptor subunit epsilon-2
- Genomic Location:
- Chr 6: 135679813-136123529
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AAANWWTGC_UNKNOWN , AAAYRNCTG_UNKNOWN , EVI1_06 , RSRFC4_01 , YY1_01 , GATA1_01 , IK1_01 , IK2_01 , IK3_01 , GATA1_03
- miRNA binding sites
(Source: TargetScan):
| Transcripts Names |
|---|
| NM_008171 |
| XM_011241220 |
| XM_006505574 |
| XM_011241221 |
| XM_006505573 |
| XM_006505575 |
| XM_017321396 |
GO Molecular Function
transmitter-gated ion channel activity | beta-catenin binding | ligand-gated calcium channel activity | neurotransmitter receptor activity | glycine binding | voltage-gated ion channel activity | cation binding | passive transmembrane transporter activity | neurotransmitter binding | transmembrane signaling receptor activity | carboxylic acid binding | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | signaling receptor binding | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | cytokine receptor binding | anion binding | amino acid binding | NMDA glutamate receptor activity | cation transmembrane transporter activity | dopamine receptor binding | signaling receptor activity | D2 dopamine receptor binding | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | protein heterodimerization activity | scaffold protein binding | extracellular ligand-gated ion channel activity | glutamate receptor activity | ion binding | cell adhesion molecule binding | protein binding | zinc ion binding | ionotropic glutamate receptor activity | metal ion transmembrane transporter activity | protein dimerization activity | interleukin-1 receptor binding | voltage-gated cation channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration | G-protein coupled receptor binding | excitatory extracellular ligand-gated ion channel activity | extracellularly glutamate-gated ion channel activity | glutamate binding | transition metal ion binding | cation channel activity | glutamate-gated calcium ion channel activity | inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | growth factor receptor binding | drug binding | calcium channel activity | organic acid binding | metal ion binding | ion channel activity | substrate-specific channel activity | glutamate receptor binding | ionotropic glutamate receptor binding | small molecule binding
GO Biological Process
transmitter-gated ion channel activity | behavioral response to pain | regulation of cysteine-type endopeptidase activity | detection of stimulus | protein heterotetramerization | behavioral fear response | intracellular signal transduction | calcium ion transmembrane import into cytosol | cytosolic calcium ion transport | regulation of localization | ligand-gated calcium channel activity | establishment of localization | negative regulation of cellular process | excitatory postsynaptic potential | detection of mechanical stimulus involved in sensory perception | defense response | response to drug | cellular chemical homeostasis | NMDA selective glutamate receptor signaling pathway | voltage-gated ion channel activity | response to antibiotic | sensory perception of mechanical stimulus | regulation of neuron death | cellular process | localization | cellular homeostasis | positive regulation of synaptic transmission | passive transmembrane transporter activity | metal ion transport | negative regulation of synapse organization | chemical synaptic transmission | regulation of neuronal synaptic plasticity | learning | macromolecule localization | response to hypoxia | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | transmembrane transporter activity | positive regulation of cellular protein metabolic process | ligand-gated ion channel activity | cellular component organization | calcium ion homeostasis | calcium ion transport into cytosol | associative learning | response to stimulus | ion gated channel activity | regulation of long-term synaptic potentiation | response to pain | positive regulation of protein metabolic process | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | positive regulation of peptidase activity | response to stress | positive regulation of cysteine-type endopeptidase activity | positive regulation of long-term synaptic potentiation | receptor clustering | cellular localization | divalent metal ion transport | response to alcohol | rhythmic process | positive regulation of proteolysis | cellular component assembly | regulation of synapse structure or activity | modulation of chemical synaptic transmission | embryo development | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | metal ion homeostasis | response to ethanol | negative regulation of dendritic spine maintenance | regulation of membrane potential | detection of abiotic stimulus | response to nitrogen compound | regulation of long-term neuronal synaptic plasticity | system development | response to oxygen levels | regulation of signal transduction | multicellular organism development | regulation of peptidase activity | calcium ion transmembrane transport | regulation of MAPK cascade | learning or memory | positive regulation of glutamate secretion | protein complex oligomerization | regulation of catalytic activity | regulation of phosphorylation | ion transmembrane transport | localization within membrane | nonassociative learning | detection of mechanical stimulus involved in sensory perception of pain | regulation of postsynaptic membrane potential | protein localization to membrane | positive regulation of secretion | nervous system process | synaptic signaling | NMDA glutamate receptor activity | cation transmembrane transporter activity | positive regulation of cellular metabolic process | cellular ion homeostasis | regulation of synapse organization | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | positive regulation of hydrolase activity | second-messenger-mediated signaling | cognition | sensory perception of pain | regulation of cellular protein metabolic process | extracellular ligand-gated ion channel activity | positive regulation of endopeptidase activity | positive regulation of neuron death | startle response | protein tetramerization | response to toxic substance | regulation of glutamate secretion | cation homeostasis | sensory organ development | chordate embryonic development | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | cellular calcium ion homeostasis | homeostatic process | regulation of protein phosphorylation | suckling behavior | embryo development ending in birth or egg hatching | positive regulation of transport | positive regulation of molecular function | calcium-mediated signaling | cation transmembrane transport | protein-containing complex assembly | multicellular organismal response to stress | fear response | response to organic substance | negative regulation of cell projection organization | ionotropic glutamate receptor activity | response to mechanical stimulus | detection of stimulus involved in sensory perception | metal ion transmembrane transporter activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | voltage-gated cation channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration | regulation of postsynaptic cytosolic calcium ion concentration | cellular protein localization | chemical homeostasis | calcium ion transport | regulation of secretion | behavior | positive regulation of cell death | positive regulation of amino acid transport | animal organ development | positive regulation of ion transport | excitatory extracellular ligand-gated ion channel activity | extracellularly glutamate-gated ion channel activity | ion homeostasis | regulation of phosphate metabolic process | inorganic cation transmembrane transport | regulation of dendritic spine maintenance | detection of mechanical stimulus | positive regulation of organic acid transport | regulation of postsynapse organization | regulation of protein kinase A signaling | cation channel activity | memory | sensory perception | regulation of cell communication | transmembrane transport | action potential | glutamate-gated calcium ion channel activity | signaling | feeding behavior | inorganic cation transmembrane transporter activity | neuromuscular process | protein localization | voltage-gated channel activity | protein heterooligomerization | regulation of endopeptidase activity | cation transport | cellular macromolecule localization | channel activity | glutamate receptor signaling pathway | regulation of ion transport | developmental process | calcium channel activity | positive regulation of anion transport | behavioral defense response | sensitization | regulation of transport | response to organonitrogen compound | cellular metal ion homeostasis | regulation of anion transport | ion channel activity | in utero embryonic development | positive regulation of metabolic process | regulation of synaptic plasticity | ion transport | regulation of cell projection organization | long-term synaptic potentiation | regulation of cell death | ionotropic glutamate receptor signaling pathway | divalent inorganic cation homeostasis | substrate-specific channel activity | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
presynaptic membrane | supramolecular fiber | synaptic cleft | dendritic spine | exocytic vesicle | integral component of membrane | dendrite | synapse | neuron projection | somatodendritic compartment | sarcomere | postsynaptic specialization membrane | cytoplasmic vesicle | cell body | cell | neuronal cell body | plasma membrane protein complex | distal axon | intrinsic component of membrane | synaptic membrane | terminal bouton | myofibril | cytoplasm | intracellular organelle | NMDA selective glutamate receptor complex | receptor complex | dendritic tree | contractile fiber | presynapse | protein-containing complex | cell projection | secretory vesicle | postsynaptic membrane | endomembrane system | neuron spine | postsynapse | plasma membrane | postsynaptic density membrane | vesicle | transport vesicle | postsynaptic density | asymmetric synapse | integral component of plasma membrane | synaptic vesicle | extracellular region | membrane-bounded organelle | organelle | postsynaptic specialization | I band | axon terminus | apical dendrite | cell periphery | axon | ionotropic glutamate receptor complex | transmembrane transporter complex | neuron projection terminus | cation channel complex | ion channel complex | Z disc | intracellular vesicle | cell surface | intracellular | cell junction | membrane | supramolecular complex | intrinsic component of plasma membrane
