QuickView for GRK5;jsessionid=3DB23E2F2780610F78B29D86F9D142CE;jsessionid=3E7DFF9A43A2EB536DA4887EF143590B (gene)
- Gene Symbol:
- Grk5
Rattus norvegicus - Full name:
- G protein-coupled receptor kinase 5
- Synonyms:
- Gprk5, G protein-coupled receptor kinase 5, g protein-coupled receptor kinase GRK5
- Genomic Location:
- Chr 1: 267495534-267693144
- Description:
-
plays a role in homologous desentization of the thyrotropin receptor
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
P300_01 , NFKAPPAB65_01 , CREL_01 , NFKAPPAB_01 , MZF1_02 , IK2_01 , SRY_01 , AP2_Q6 , NFKB_Q6 , NFKB_C
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
ribonucleotide binding | lipid binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | G-protein coupled receptor kinase activity | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | beta-adrenergic receptor kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
negative regulation of G-protein coupled receptor protein signaling pathway | response to isoquinoline alkaloid | regulation of programmed cell death | negative regulation of cellular process | cell differentiation | response to drug | cellular process | response to morphine | negative regulation of signaling | negative regulation of apoptotic process | regulation of cell cycle | regulation of cellular process | regulation of apoptotic process | response to stimulus | response to cocaine | regulation of cell proliferation | protein serine/threonine kinase activity | programmed cell death | G-protein coupled receptor signaling pathway | protein modification process | macromolecule modification | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | response to nitrogen compound | apoptotic process | G-protein coupled receptor kinase activity | nitrogen compound metabolic process | regulation of signal transduction | Wnt signaling pathway | phosphorus metabolic process | tachykinin receptor signaling pathway | response to ammonium ion | protein autophosphorylation | fat cell differentiation | phosphorylation | response to xenobiotic stimulus | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | positive regulation of cell proliferation | negative adaptation of signaling pathway | protein metabolic process | response to organic substance | beta-adrenergic receptor kinase activity | cell surface receptor signaling pathway | metabolic process | negative regulation of programmed cell death | protein kinase activity | organic substance metabolic process | cell death | desensitization of G-protein coupled receptor protein signaling pathway | response to alkaloid | regulation of cell communication | negative regulation of signal transduction | signaling | response to organic cyclic compound | cellular protein metabolic process | regulation of G-protein coupled receptor protein signaling pathway | kinase activity | developmental process | cellular protein modification process | response to organonitrogen compound | response to anesthetic | cellular metabolic process | regulation of cell death | negative regulation of cell death | signal transduction | regulation of signaling | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | endomembrane system | nucleoplasm | plasma membrane | nuclear envelope | nuclear speck | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane
