QuickView for Gb3;jsessionid=65420DB30BDAE4C8F15520F10045F0CF;jsessionid=9CFEFE3B1354ADF57632EF855E06FBA9;jsessionid=F50633C4416EFB33AE88DCE39CA923E0 (gene)

Gene Symbol:

A4GALT Homo sapiens

Full name:

alpha 1,4-galactosyltransferase (P blood group)

Synonyms:

A14GALT, A4GALT1, Gb3S, P(k), P1, P1PK, PK, lactosylceramide 4-alpha-galactosyltransferase, CD77 synthase, GB3 synthase, P blood group (P one antigen), P one antigen (P blood group), P(k) antigen synthase, P1/Pk synthase, UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase, alpha 14-galactosyltransferase, alpha-1,4-N-acetylglucosaminyltransferase, alpha-1,4-galactosyltransferase, alpha4Gal-T1, globotriaosylceramide synthase, truncated alpha 1,4-galactosyltransferase

Genomic Location:

Chr 22: 41418071-41446820

Description:

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced...

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The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CAGGTG_E12_Q6

Cytogenetic Map:

22q13.2

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