QuickView for GnRH1;jsessionid=BE8B2D365A48017BD5B131D641C8E232;jsessionid=78B4FC29FA393493BC0095BBB5D4580E (gene)

Gene Symbol:

Gnrh1 Mus musculus

Full name:

gonadotropin releasing hormone 1

Synonyms:

Gnrh, Gnrh2, LHRH, Lhrh1, Lnrh, hpg, progonadoliberin-1, gonadotropin releasing hormone 2, luteinizing hormone-releasing hormone I, progonadoliberin I

Genomic Location:

Chr 14: 68364403-68367348

Description:

This gene encodes hypophysiotropic peptides belonging to the family of gonadotropin-releasing hormones that stimulate the release of gonadotropins and suppress secretion of prolactin from the pituitary gland. The encoded protein is proteolytically processed to generate two biologically active mature peptides. A deletional mutation encompassing the ...

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This gene encodes hypophysiotropic peptides belonging to the family of gonadotropin-releasing hormones that stimulate the release of gonadotropins and suppress secretion of prolactin from the pituitary gland. The encoded protein is proteolytically processed to generate two biologically active mature peptides. A deletional mutation encompassing the distal half of this gene in mice resulting in the loss of the encoded protein leads to hypogonadism and infertility. Alternative splicing results in multiple transcript variants.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

EN1_01 ,  YCATTAA_UNKNOWN ,  YKACATTT_UNKNOWN ,  CAGGTA_AREB6_01

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