QuickView for Gpr161;jsessionid=EBB2DA4731369CBF458940F7594CACFF;jsessionid=BF8896F94EA21DF03C5B4E860DBD10FB;jsessionid=58B462FEDC2233C09EE22902403EAB9C (gene)

Gene Symbol:

GPR161 Homo sapiens

Full name:

G protein-coupled receptor 161

Synonyms:

RE2, G-protein coupled receptor 161, G-protein coupled receptor RE2

Genomic Location:

Chr 1: 166320621-166372248

Description:

The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer.

The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RORA1_01 ,  E2F_Q2 ,  CTTTGT_LEF1_Q2 ,  HOX13_01

Cytogenetic Map:

1q24.2

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