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QuickView for HDAC8;jsessionid=F949DE42DBAA5C59033927D316DDCF25;jsessionid=3A716C3FF7BB77F3E755A08C4018E71D (gene)


Gene Symbol:
Hdac8 Mus musculus Mus musculus
Full name:
histone deacetylase 8
Synonyms:
2610007D20Rik, histone deacetylase 8, HD8
Genomic Location:
Chr X: 99479979-99700487
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

cation binding | histone deacetylase activity (H3-K14 specific) | NAD-dependent histone deacetylase activity (H3-K14 specific) | hydrolase activity | protein deacetylase activity | catalytic activity | chromatin binding | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | Hsp70 protein binding | NAD-dependent protein deacetylase activity | histone deacetylase activity | ion binding | NAD-dependent histone deacetylase activity | protein binding | transcription factor binding | Hsp90 protein binding | deacetylase activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | heat shock protein binding | metal ion binding

GO Biological Process

RNA metabolic process | regulation of cell cycle process | regulation of cellular localization | regulation of localization | negative regulation of cellular process | histone modification | histone deacetylation | regulation of organelle organization | regulation of chromosome segregation | cellular process | chromatin organization | regulation of cell cycle | histone deacetylase activity (H3-K14 specific) | negative regulation of cellular metabolic process | regulation of binding | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | regulation of cellular protein localization | chromosome segregation | NAD-dependent histone deacetylase activity (H3-K14 specific) | cellular nitrogen compound biosynthetic process | regulation of protein ubiquitination | cellular nitrogen compound metabolic process | regulation of DNA binding | negative regulation of metabolic process | protein modification process | protein deacetylase activity | cellular biosynthetic process | macromolecule modification | histone H3 deacetylation | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of protein stability | NAD-dependent protein deacetylase activity | sister chromatid segregation | regulation of telomere maintenance | regulation of gene expression | histone deacetylase activity | cell cycle | regulation of nitrogen compound metabolic process | regulation of cohesin loading | biosynthetic process | protein deacetylation | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | NAD-dependent histone deacetylase activity | nuclear chromosome segregation | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of RNA metabolic process | negative regulation of protein ubiquitination | regulation of sister chromatid cohesion | protein metabolic process | regulation of sister chromatid segregation | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of cellular protein metabolic process | gene expression | regulation of chromosome organization | transcription, DNA-templated | regulation of protein localization to chromatin | negative regulation of protein metabolic process | covalent chromatin modification | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | organelle organization | sister chromatid cohesion | cellular protein modification process | heterocycle metabolic process | chromosome organization | cellular metabolic process | regulation of protein localization | regulation of cellular component organization | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | histone deacetylase complex | nucleoplasm | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | intracellular | membrane