QuickView for HMGCR;jsessionid=8831FA6B9DCA8B4344ED1C517F3F53A2;jsessionid=F37D4DA474AB9D111DF687D95B790E31 (gene)
- Gene Symbol:
- HMGCR
Gallus gallus - Full name:
- 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
- Synonyms:
- HMGR, RCJMB04_14m24
- Genomic Location:
- Chr Z: 23472984-23487423
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
hydroxymethylglutaryl-CoA reductase (NADPH) activity | oxidoreductase activity, acting on CH-OH group of donors | NADP binding | cofactor binding | nucleotide binding | coenzyme binding | catalytic activity | anion binding | ion binding | organic cyclic compound binding | hydroxymethylglutaryl-CoA reductase activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | NADPH binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
negative regulation of phosphorylation | purine ribonucleotide metabolic process | response to radiation | hydroxymethylglutaryl-CoA reductase (NADPH) activity | negative regulation of MAPK cascade | oxidoreductase activity, acting on CH-OH group of donors | isoprenoid biosynthetic process | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | negative regulation of protein phosphorylation | sterol metabolic process | cellular process | nucleotide metabolic process | negative regulation of signaling | visual learning | ribose phosphate metabolic process | learning | ribonucleotide metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | steroid biosynthetic process | cellular component organization | cellular lipid metabolic process | associative learning | response to stimulus | purine nucleotide metabolic process | negative regulation of protein kinase activity | alcohol metabolic process | coenzyme A metabolic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cofactor metabolic process | cellular component assembly | cellular biosynthetic process | organic hydroxy compound metabolic process | response to light stimulus | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of MAPK cascade | phosphorus metabolic process | learning or memory | protein complex oligomerization | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of phosphorylation | nervous system process | organophosphate metabolic process | sterol biosynthetic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | negative regulation of protein serine/threonine kinase activity | nucleobase-containing small molecule metabolic process | cognition | biosynthetic process | cholesterol biosynthetic process | regulation of cellular protein metabolic process | lipid biosynthetic process | protein tetramerization | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | negative regulation of MAP kinase activity | hydroxymethylglutaryl-CoA reductase activity | protein-containing complex assembly | visual behavior | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | metabolic process | cholesterol metabolic process | oxidation-reduction process | behavior | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of cellular protein metabolic process | regulation of phosphate metabolic process | negative regulation of protein metabolic process | steroid metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | isoprenoid metabolic process | carbohydrate derivative metabolic process | heterocycle metabolic process | cellular metabolic process | oxidoreductase activity | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
peroxisomal membrane | integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | peroxisome | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
