QuickView for HMOX1;jsessionid=6035109A7548FDD017160F3ECFF1C66B;jsessionid=BE217910626D4CDCA418883C23310E45;jsessionid=EAF9549AB385DD63A8DD61D66F4EB405 (gene)

Gene Symbol:

HMOX1 Homo sapiens

Full name:

heme oxygenase 1

Synonyms:

HMOX1D, HO-1, HSP32, bK286B10, heme oxygenase 1, heat shock protein, 32-kD, heme oxygenase (decycling) 1

Genomic Location:

Chr 22: 34107087-34120194

Description:

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible...

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Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TCANNTGAY_SREBP1_01 ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  TGTGTGA_MIR377 ,  CREB_Q3 ,  USF_C ,  USF_01 ,  NMYC_01 ,  USF_Q6_01 ,  CAGCTG_AP4_Q5 ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-377

Cytogenetic Map:

22q12.3

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