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QuickView for HSP90AA1;jsessionid=3F2F72A670E9540978E31C8AB0E43225;jsessionid=31D387E57078850A073D8537FA66DDE5 (gene)


Gene Symbol:
Hsp90aa1 Rattus norvegicus Rattus norvegicus
Full name:
heat shock protein 90, alpha (cytosolic), class A member 1
Synonyms:
Hsp86, Hsp90, Hspca, heat shock protein HSP 90-alpha, HSP 86, heat shock 86 kDa, heat shock protein 1, alpha, heat shock protein 86
Genomic Location:
Chr 6: 135413616-135419147
Description:
a molecular chaperone; involved in sequestering damaged proteins and in ATP-dependent folding of proteins
Orthologs:
Homo sapiens Mus musculus D. melanogaster Saccharomyces cerevisiae Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Danio rerio Pan troglodytes
External Links:
Entrez Gene


Transcripts Names
NM_175761
Protein Names
P82995
Q91XW0



GO Molecular Function

kinase binding | guanyl ribonucleotide binding | GTPase binding | ribonucleoside binding | protein kinase binding | enzyme binding | nucleic acid binding | ribonucleotide binding | DNA polymerase binding | disordered domain specific binding | mRNA binding | nucleotide binding | signaling receptor binding | hydrolase activity | pyrimidine ribonucleotide binding | carbohydrate derivative binding | unfolded protein binding | ATPase activity | pyrophosphatase activity | CTP binding | molecular function regulator | catalytic activity | ion channel binding | protein domain specific binding | ATP binding | ubiquitin-like protein ligase binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | tau protein binding | sulfonylurea receptor binding | purine nucleotide binding | identical protein binding | Rho GDP-dissociation inhibitor binding | adenyl deoxyribonucleotide binding | TPR domain binding | scaffold protein binding | ion binding | organic cyclic compound binding | protein tyrosine kinase binding | purine nucleoside binding | UTP binding | purine ribonucleoside triphosphate binding | GDP-dissociation inhibitor binding | protein tyrosine kinase activity | protein binding | protein homodimerization activity | protein phosphatase binding | ubiquitin protein ligase binding | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | GTP binding | phosphotransferase activity, alcohol group as acceptor | nitric-oxide synthase regulator activity | hydrolase activity, acting on acid anhydrides | protein kinase activity | transferase activity | nucleoside binding | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | dATP binding | drug binding | kinase activity | phosphatase binding | histone deacetylase binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | pyrimidine nucleotide binding | small molecule binding | RNA binding

GO Biological Process

positive regulation of heart contraction | multicellular organismal movement | cell morphogenesis | regulation of muscle system process | positive regulation of macromolecule biosynthetic process | telomere maintenance | regulation of intracellular protein transport | positive regulation of blood circulation | positive regulation of cellular component organization | cell motility | neuron projection morphogenesis | regulation of cellular localization | protein stabilization | protein localization to mitochondrion | regulation of localization | peptidyl-amino acid modification | establishment of localization | regulation of nitric oxide biosynthetic process | neuron migration | regulation of protein import | cell differentiation | nervous system development | positive regulation of protein catabolic process | response to drug | cell part morphogenesis | positive regulation of tau-protein kinase activity | neurogenesis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | generation of neurons | membrane organization | response to antibiotic | intracellular transport | neuron projection extension | positive regulation of cellular biosynthetic process | cellular process | telomere maintenance via telomerase | organic substance catabolic process | musculoskeletal movement | central nervous system neuron axonogenesis | localization | cell projection morphogenesis | protein transport | developmental growth | positive regulation of peptidyl-serine phosphorylation | neuron development | positive regulation of reactive oxygen species metabolic process | central nervous system neuron differentiation | establishment of protein localization to mitochondrion | positive regulation of telomerase activity | positive regulation of protein kinase activity | macromolecule localization | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | chaperone-mediated autophagy | anatomical structure homeostasis | positive regulation of lamellipodium assembly | regulation of protein kinase B signaling | regulation of cellular process | positive regulation of lamellipodium organization | regulation of metabolic process | catabolic process | regulation of protein complex assembly | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular aromatic compound metabolic process | establishment of cell polarity | cellular component organization | positive regulation of cellular protein catabolic process | muscle contraction | outer mitochondrial membrane organization | response to stimulus | cell morphogenesis involved in neuron differentiation | regulation of cellular protein localization | positive regulation of nitric oxide metabolic process | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | response to cold | response to cocaine | response to salt stress | response to stress | intracellular protein transport | positive regulation of cellular protein localization | cellular nitrogen compound biosynthetic process | establishment of protein localization to mitochondrial membrane | regulation of protein ubiquitination | regulation of blood circulation | programmed cell death | chaperone-mediated protein transport involved in chaperone-mediated autophagy | cellular localization | response to temperature stimulus | cellular nitrogen compound metabolic process | telomere organization | regulation of protein transport | regulation of cellular component size | cellular component assembly | protein modification process | regulation of peptide transport | cellular biosynthetic process | mitochondrion organization | macromolecule modification | telomere maintenance via telomere lengthening | regulation of intracellular transport | molecular function regulator | regulation of neurotransmitter levels | locomotion | response to nitrogen compound | central nervous system neuron development | apoptotic process | positive regulation of reactive oxygen species biosynthetic process | regulation of cell projection assembly | system development | nitrogen compound metabolic process | regulation of signal transduction | regulation of protein stability | multicellular organism development | cell migration | phosphorus metabolic process | regulation of tau-protein kinase activity | regulation of muscle contraction | positive regulation of protein kinase B signaling | regulation of catalytic activity | regulation of phosphorylation | telomerase holoenzyme complex assembly | DNA biosynthetic process | protein localization to membrane | axon development | organic substance transport | protein catabolic process | positive regulation of intracellular protein transport | RNA-dependent DNA biosynthetic process | regulation of protein import into nucleus, translocation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of telomerase activity | response to ammonium ion | mitochondrial transport | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | positive regulation of cell projection organization | peptide transport | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | cellular amide metabolic process | axonogenesis | protein localization to organelle | positive regulation of protein localization to nucleus | biosynthetic process | response to osmotic stress | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | phosphorylation | cellular protein-containing complex assembly | response to xenobiotic stimulus | regulation of heart contraction | protein phosphorylation | cell morphogenesis involved in differentiation | establishment or maintenance of cell polarity | phosphate-containing compound metabolic process | autophagy | protein import | regulation of striated muscle contraction | mitochondrial membrane organization | response to estrogen | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of DNA biosynthetic process | regulation of cardiac muscle contraction | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | positive regulation of establishment of protein localization | regulation of protein phosphorylation | peptide metabolic process | positive regulation of transport | striated muscle contraction | protein tyrosine kinase activity | positive regulation of molecular function | regulation of nucleocytoplasmic transport | establishment of protein localization to membrane | neuron differentiation | protein-containing complex assembly | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of protein import into nucleus | regulation of kinase activity | DNA metabolic process | chaperone-mediated protein complex assembly | axon extension | regulation of intracellular signal transduction | establishment of protein localization to organelle | anatomical structure development | developmental growth involved in morphogenesis | positive regulation of cardiac muscle contraction | cell projection organization | metabolic process | regulation of protein catabolic process | cellular protein localization | positive regulation of striated muscle contraction | amide transport | nitric-oxide synthase regulator activity | nucleobase-containing compound metabolic process | protein kinase activity | neuron projection development | positive regulation of muscle contraction | positive regulation of cellular component biogenesis | organic substance metabolic process | protein folding | cell death | ribonucleoprotein complex assembly | positive regulation of kinase activity | response to heat | regulation of phosphate metabolic process | response to alkaloid | establishment of protein localization | positive regulation of intracellular transport | positive regulation of protein transport | cardiac muscle cell apoptotic process | regulation of reactive oxygen species biosynthetic process | regulation of peptidyl-serine phosphorylation | organonitrogen compound catabolic process | positive regulation of protein import into nucleus, translocation | regulation of cell communication | transmembrane transport | response to organic cyclic compound | cell development | skeletal muscle contraction | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cell size | enzyme regulator activity | anatomical structure morphogenesis | cellular macromolecule localization | cellular macromolecule biosynthetic process | positive regulation of plasma membrane bounded cell projection assembly | positive regulation of protein import into nucleus | protein targeting to mitochondrion | positive regulation of DNA metabolic process | kinase activity | developmental process | organelle organization | regulation of DNA biosynthetic process | positive regulation of protein import | positive regulation of cell size | cellular protein modification process | regulation of transport | regulation of reactive oxygen species metabolic process | chaperone-mediated protein transport | developmental cell growth | positive regulation of protein polymerization | regulation of lamellipodium assembly | response to organonitrogen compound | heterocycle metabolic process | positive regulation of nitric oxide biosynthetic process | central nervous system development | protein transmembrane transport | response to anesthetic | positive regulation of metabolic process | chromosome organization | protein targeting | ribonucleoprotein complex biogenesis | regulation of cell projection organization | cellular metabolic process | regulation of protein localization | regulation of protein complex stability | muscle cell apoptotic process | positive regulation of nucleocytoplasmic transport | regulation of cellular component organization | muscle system process | positive regulation of signaling | regulation of signaling | macromolecule metabolic process | multicellular organismal process | protein import into mitochondrial outer membrane | regulation of phosphorus metabolic process

GO Cellular Component

sperm flagellum | brush border | dendrite | intracellular membrane-bounded organelle | apical plasma membrane | neuron projection | extracellular matrix | ruffle | somatodendritic compartment | organelle membrane | cell projection membrane | cytoplasmic vesicle | sperm mitochondrial sheath | cell body | cell | neuronal cell body | distal axon | dendrite terminus | ruffle membrane | cytoplasm | intracellular organelle | 9+2 motile cilium | motile cilium | brush border membrane | dendritic tree | leading edge membrane | apical part of cell | melanosome | protein-containing complex | cell projection | plasma membrane | cell leading edge | cilium | vacuole | vesicle | perinuclear region of cytoplasm | site of polarized growth | sperm plasma membrane | lytic vacuole | axonal growth cone | extracellular region | membrane-bounded organelle | nucleus | organelle | lysosome | cell periphery | axon | basolateral plasma membrane | growth cone | cytosol | intracellular vesicle | cell surface | dendritic growth cone | intracellular | myelin sheath | lysosomal membrane | membrane | vacuolar membrane