QuickView for HTR4;jsessionid=9125E3998FC1E17580666DCCC86C125D;jsessionid=56F2E191AACC0CA937690E79A06D17C2;jsessionid=4EEE542712F7EE9B82AF03D5817D1E0E;jsessionid=CDF601E2405C8112692191EAC7D3B547;jsessionid=8B33E773FA2F5E61186DDF5BD700F16A (gene)

Gene Symbol:

HTR4 Homo sapiens

Full name:

5-hydroxytryptamine receptor 4

Synonyms:

5-HT4, 5-HT4R, 5-hydroxytryptamine receptor 4, 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled, 5-hydroxytryptamine receptor 4 transcript variant b2, 5-hydroxytryptamine receptor 4 transcript variant b3, cardiac 5-HT4 receptor

Genomic Location:

Chr 5: 147810788-148013934

Description:

This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitter...

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This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NKX25_01 ,  CDP_01 ,  AR_Q6 ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  ATGCTGC_MIR103_MIR107 ,  OCT1_06 ,  POU3F2_02 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-331 ,  Predicted Gene Targets for miR-503 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182

Cytogenetic Map:

5q32

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