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QuickView for Hsd3b6;jsessionid=9DA6BE61D5EB9A592494EE6414336E4B (gene)


Gene Symbol:
Hsd3b2 Rattus norvegicus Rattus norvegicus
Full name:
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Synonyms:
Hsd3b1, Hsd3b2l1, Hsd3b6, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4, 3 beta-hydroxysteroid dehydrogenase 6, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type IV, 3-beta-HSD IV, Hydroxy-delta-5-steroid dehydrogenase 3 beta- and steroid delta-isomerase, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6, hydroxysteroid dehydrogenase-6 delta<5>-3-beta
Genomic Location:
Chr 2: 193337342-193346799
Description:
enzyme responsible for the production of progesterone as well as the precursors of androgens, estrogens, glucocorticoids and mineralcorticoids
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene


Transcripts Names
NM_017265
Protein Names
Q62878
Q5FVK0



GO Molecular Function

oxidoreductase activity, acting on CH-OH group of donors | steroid dehydrogenase activity | intramolecular oxidoreductase activity, transposing C=C bonds | 3-beta-hydroxy-delta5-steroid dehydrogenase activity | isomerase activity | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | testosterone dehydrogenase [NAD(P)] activity | catalytic activity | intramolecular oxidoreductase activity | cholesterol dehydrogenase activity | steroid delta-isomerase activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | oxidoreductase activity

GO Biological Process

brain development | oxidoreductase activity, acting on CH-OH group of donors | steroid dehydrogenase activity | developmental process involved in reproduction | regulation of localization | gonad development | hippocampus development | response to hormone | 3-beta-hydroxy-delta5-steroid dehydrogenase activity | response to metal ion | cell differentiation | nervous system development | cellular process | Leydig cell differentiation | reproductive system development | response to corticosterone | response to inorganic substance | organic cyclic compound metabolic process | steroid biosynthetic process | development of primary sexual characteristics | head development | response to stimulus | androgen biosynthetic process | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | reproduction | response to alcohol | androgen metabolic process | testosterone dehydrogenase [NAD(P)] activity | negative regulation of transport | cellular biosynthetic process | system development | reproductive process | multicellular organism development | hormone biosynthetic process | lipid metabolic process | regulation of hormone levels | telencephalon development | response to ketone | response to lipid | response to corticosteroid | biosynthetic process | response to cadmium ion | negative regulation of ion transport | lipid biosynthetic process | limbic system development | development of primary male sexual characteristics | response to organic substance | male sex differentiation | anatomical structure development | negative regulation of iron ion transport | metabolic process | response to mineralocorticoid | cholesterol dehydrogenase activity | oxidation-reduction process | male gonad development | organic substance metabolic process | animal organ development | forebrain development | pallium development | C21-steroid hormone metabolic process | response to gonadotropin | steroid metabolic process | response to organic cyclic compound | hormone metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | reproductive structure development | regulation of ion transport | developmental process | C21-steroid hormone biosynthetic process | regulation of transport | response to lead ion | central nervous system development | cellular metabolic process | sex differentiation | oxidoreductase activity | response to steroid hormone | response to glucocorticoid | multicellular organismal process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane