QuickView for Hspa5;jsessionid=C1144D6B1B9207F271A23997F1BA1607 (gene)
- Gene Symbol:
- HSPA5
Gallus gallus - Full name:
- heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
- Synonyms:
- GRP78
- Genomic Location:
- Chr 17: 10313902-10317954
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Bos taurus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
enzyme binding | protein-containing complex binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | unfolded protein binding | ATPase activity | pyrophosphatase activity | catalytic activity | ribonucleoprotein complex binding | protein domain specific binding | ATP binding | ubiquitin-like protein ligase binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | ion binding | organic cyclic compound binding | ribosome binding | protein binding involved in protein folding | purine ribonucleoside triphosphate binding | protein binding | misfolded protein binding | ubiquitin protein ligase binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heat shock protein binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
response to extracellular stimulus | brain development | regulation of IRE1-mediated unfolded protein response | cellular response to glucose starvation | positive regulation of locomotion | response to nutrient levels | response to endoplasmic reticulum stress | response to cytokine | 'de novo' posttranslational protein folding | regulation of endoplasmic reticulum unfolded protein response | proteolysis | regulation of localization | regulation of programmed cell death | establishment of localization | regulation of transforming growth factor beta receptor signaling pathway | negative regulation of cellular process | negative regulation of IRE1-mediated unfolded protein response | nervous system development | cellular response to extracellular stimulus | cerebellum morphogenesis | positive regulation of cellular component movement | cellular process | organic substance catabolic process | regulation of cell motility | localization | negative regulation of protein homodimerization activity | proteolysis involved in cellular protein catabolic process | chaperone-mediated protein folding | negative regulation of signaling | protein localization to endoplasmic reticulum | macromolecule localization | endoplasmic reticulum unfolded protein response | negative regulation of response to endoplasmic reticulum stress | negative regulation of apoptotic process | cellular response to starvation | positive regulation of nitrogen compound metabolic process | regulation of binding | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | positive regulation of cellular protein metabolic process | cellular response to unfolded protein | response to topologically incorrect protein | cellular response to topologically incorrect protein | anatomical structure arrangement | head development | response to stimulus | metencephalon development | positive regulation of protein metabolic process | response to stress | regulation of response to endoplasmic reticulum stress | toxin transport | regulation of protein ubiquitination | response to starvation | regulation of protein homodimerization activity | cellular protein catabolic process | cellular localization | response to temperature stimulus | proteasomal protein catabolic process | maintenance of protein localization in organelle | negative regulation of endoplasmic reticulum unfolded protein response | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | negative regulation of cellular response to transforming growth factor beta stimulus | regulation of cellular response to stress | response to nitrogen compound | system development | cellular response to nutrient levels | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | cerebellum development | ER-nucleus signaling pathway | cellular response to stress | protein catabolic process | cellular response to heat | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of cell migration | negative regulation of cellular response to growth factor stimulus | regulation of cellular component movement | protein localization to organelle | negative regulation of binding | positive regulation of cell migration | cellular response to cytokine stimulus | 'de novo' protein folding | regulation of cellular protein metabolic process | hindbrain development | maintenance of protein location | cell communication | negative regulation of protein binding | regulation of cellular metabolic process | regulation of protein metabolic process | protein binding involved in protein folding | regulation of locomotion | regulation of cellular response to growth factor stimulus | proteasome-mediated ubiquitin-dependent protein catabolic process | ER overload response | ERAD pathway | cellular response to interleukin-4 | protein metabolic process | negative regulation of transforming growth factor beta receptor signaling pathway | positive regulation of protein modification process | response to organic substance | cellular macromolecule catabolic process | anatomical structure development | metabolic process | negative regulation of programmed cell death | cellular protein localization | cerebellar cortex development | hindbrain morphogenesis | organic substance metabolic process | protein folding | cerebellar Purkinje cell layer development | maintenance of protein localization in endoplasmic reticulum | animal organ development | cerebellum structural organization | response to heat | maintenance of protein location in cell | hindbrain structural organization | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of protein binding | protein localization | cellular protein metabolic process | response to unfolded protein | anatomical structure morphogenesis | cellular macromolecule localization | response to biotic stimulus | chaperone cofactor-dependent protein refolding | developmental process | response to organonitrogen compound | protein refolding | central nervous system development | ubiquitin-dependent ERAD pathway | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | regulation of cell death | positive regulation of cell motility | modification-dependent protein catabolic process | negative regulation of cell death | positive regulation of protein ubiquitination | signal transduction | regulation of signaling | macromolecule metabolic process | maintenance of location in cell | multicellular organismal process | response to interleukin-4
GO Cellular Component
endoplasmic reticulum chaperone complex | endoplasmic reticulum-Golgi intermediate compartment | integral component of membrane | intracellular membrane-bounded organelle | COP9 signalosome | cell | integral component of endoplasmic reticulum membrane | intrinsic component of membrane | cytoplasm | intracellular organelle | intrinsic component of endoplasmic reticulum membrane | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | plasma membrane | midbody | endoplasmic reticulum lumen | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cell surface | intracellular | myelin sheath | membrane
