QuickView for IGF-I;jsessionid=E15DF64F0316FAF0B3FFED7594F601BB;jsessionid=FC4490413425BDA0AE0EFA63EBC383B4 (gene)

GO Molecular Function

protein-containing complex binding | signaling receptor binding | hormone activity | molecular function regulator | integrin binding | cell adhesion molecule binding | protein binding | insulin receptor binding | receptor regulator activity | growth factor activity | receptor ligand activity | insulin-like growth factor receptor binding

GO Biological Process

positive regulation of smooth muscle cell proliferation | negative regulation of smooth muscle cell apoptotic process | response to insulin-like growth factor stimulus | positive regulation of glycogen biosynthetic process | positive regulation of striated muscle cell differentiation | inner ear morphogenesis | regulation of muscle system process | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | regulation of intracellular protein transport | positive regulation of Ras protein signal transduction | positive regulation of cellular component organization | regulation of cellular localization | negative regulation of peptide secretion | positive regulation of ATP metabolic process | intracellular signal transduction | regulation of cell development | protein stabilization | regulation of localization | positive regulation of striated muscle tissue development | positive regulation of embryonic development | regulation of carbohydrate metabolic process | regulation of programmed cell death | regulation of oogenesis | regulation of cardiac muscle cell differentiation | positive regulation of peptidyl-tyrosine phosphorylation | regulation of immune system process | response to hormone | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | regulation of MAP kinase activity | positive regulation of lymphocyte activation | bone development | regulation of heart growth | regulation of protein import | cell differentiation | positive regulation of epithelial cell proliferation | positive regulation of fibroblast proliferation | bone mineralization | striated muscle cell development | nervous system development | negative regulation of mitochondrion organization | positive regulation of protein catabolic process | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | negative regulation of protein secretion | regulation of organelle organization | positive regulation of cellular component movement | regulation of peptide hormone secretion | generation of neurons | positive regulation of protein secretion | positive regulation of vascular smooth muscle cell proliferation | regulation of neuron death | regulation of oocyte development | positive regulation of cellular biosynthetic process | cellular process | positive regulation of glycoprotein biosynthetic process | regulation of glucose import | regulation of cell motility | regulation of glycolytic process | regulation of calcium-mediated signaling | negative regulation of signaling | developmental growth | regulation of cell growth involved in cardiac muscle cell development | myotube cell development | regulation of mitotic nuclear division | regulation of embryonic development | regulation of striated muscle tissue development | positive regulation of protein kinase activity | negative regulation of apoptotic process | negative regulation of secretion | regulation of cell cycle | positive regulation of catalytic activity | regulation of tyrosine phosphorylation of STAT protein | regulation of multicellular organism growth | negative regulation of release of cytochrome c from mitochondria | positive regulation of nitrogen compound metabolic process | negative regulation of hormone secretion | negative regulation of establishment of protein localization | tissue development | regulation of binding | regulation of cell differentiation | positive regulation of cardiac muscle hypertrophy | positive regulation of muscle cell differentiation | muscle structure development | muscle cell differentiation | negative regulation of apoptotic signaling pathway | regeneration | glycoprotein biosynthetic process | regulation of cellular process | positive regulation of cell growth | regulation of osteoblast differentiation | regulation of apoptotic process | regulation of metabolic process | positive regulation of activated T cell proliferation | cranial nerve morphogenesis | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | insulin-like growth factor receptor signaling pathway | MAPK cascade | cranial nerve development | regulation of peptide secretion | response to stimulus | negative regulation of protein transport | muscle cell development | regulation of glycoprotein biosynthetic process | regulation of cellular protein localization | regulation of peptidyl-tyrosine phosphorylation | regulation of insulin secretion | positive regulation of immune system process | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | vestibulocochlear nerve formation | positive regulation of phosphatidylinositol 3-kinase signaling | response to stress | positive regulation of JAK-STAT cascade | positive regulation of cellular protein localization | positive regulation of lymphocyte proliferation | ganglion development | regulation of cell proliferation | negative regulation of oocyte development | response to peptide | positive regulation of cell-cell adhesion | positive regulation of glucose import | proteoglycan metabolic process | regulation of smooth muscle cell migration | phosphatidylinositol-mediated signaling | regulation of transcription regulatory region DNA binding | positive regulation of cell activation | response to temperature stimulus | positive regulation of T cell activation | positive regulation of hormone secretion | negative regulation of transport | regulation of DNA binding | hormone activity | carbohydrate derivative biosynthetic process | regulation of protein transport | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | protein modification process | regulation of peptide transport | regulation of cell adhesion | cellular biosynthetic process | embryo development | macromolecule modification | activation of protein kinase activity | regulation of intracellular transport | molecular function regulator | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | response to nitrogen compound | negative regulation of neuron apoptotic process | protein kinase B signaling | positive regulation of mononuclear cell proliferation | system development | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | negative regulation of secretion by cell | regulation of protein stability | cranial ganglion formation | multicellular organism development | regulation of MAPK cascade | neuroblast proliferation | phosphorus metabolic process | positive regulation of smooth muscle cell migration | positive regulation of muscle organ development | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | regulation of ossification | wound healing | regulation of T cell activation | positive regulation of cell cycle | regulation of activated T cell proliferation | positive regulation of mitotic cell cycle | regulation of small GTPase mediated signal transduction | regulation of gene expression | stem cell proliferation | regulation of extrinsic apoptotic signaling pathway | positive regulation of secretion | cellular response to peptide | positive regulation of intracellular protein transport | regulation of protein import into nucleus, translocation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | animal organ morphogenesis | regulation of protein localization to nucleus | positive regulation of ATP biosynthetic process | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | positive regulation of STAT cascade | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of transcription by RNA polymerase II | regulation of smooth muscle cell apoptotic process | positive regulation of cell differentiation | activation of protein kinase B activity | positive regulation of calcium-mediated signaling | negative regulation of extrinsic apoptotic signaling pathway | positive regulation of cell migration | positive regulation of glucose transmembrane transport | positive regulation of glycolytic process | cell proliferation | positive regulation of protein localization to nucleus | biosynthetic process | regulation of cellular protein metabolic process | positive regulation of trophectodermal cell proliferation | positive regulation of T cell proliferation | negative regulation of peptide hormone secretion | positive regulation of ossification | phosphorylation | inositol lipid-mediated signaling | regulation of apoptotic signaling pathway | positive regulation of cell growth involved in cardiac muscle cell development | protein phosphorylation | phosphate-containing compound metabolic process | sensory organ development | regulation of mitochondrion organization | regulation of muscle cell apoptotic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of neuron apoptotic process | positive regulation of tyrosine phosphorylation of STAT protein | cellular response to amyloid-beta | regulation of protein metabolic process | positive regulation of signal transduction | inner ear development | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | cochlea morphogenesis | positive regulation of transport | positive regulation of peptide hormone secretion | cranial ganglion development | striated muscle cell differentiation | ossification involved in bone maturation | embryonic morphogenesis | regulation of mitotic cell cycle | positive regulation of molecular function | regulation of nucleocytoplasmic transport | positive regulation of osteoblast differentiation | activation of MAPK activity | embryonic organ morphogenesis | regulation of signaling receptor activity | receptor regulator activity | positive regulation of organ growth | protein metabolic process | regulation of fibroblast proliferation | regulation of cardiac muscle hypertrophy | regulation of establishment of protein localization | positive regulation of protein modification process | regulation of growth | response to organic substance | regulation of cardiac muscle tissue development | tissue morphogenesis | regulation of protein import into nucleus | regulation of insulin-like growth factor receptor signaling pathway | regulation of JAK-STAT cascade | regulation of kinase activity | response to wounding | regulation of intracellular signal transduction | phosphatidylinositol 3-kinase signaling | anatomical structure development | cell surface receptor signaling pathway | positive regulation of small GTPase mediated signal transduction | regulation of glucose metabolic process | growth factor activity | metabolic process | positive regulation of cell development | positive regulation of glucose metabolic process | regulation of protein catabolic process | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | developmental maturation | negative regulation of programmed cell death | embryonic organ development | ear development | negative regulation of muscle cell apoptotic process | negative regulation of vascular associated smooth muscle cell apoptotic process | regulation of secretion | receptor ligand activity | organic substance metabolic process | maintenance of cell number | negative regulation of gene expression | regulation of glucose transmembrane transport | animal organ development | nerve development | gene expression | regulation of cell activation | regulation of protein secretion | vestibulocochlear nerve development | positive regulation of kinase activity | regulation of calcineurin-NFAT signaling cascade | response to heat | neural precursor cell proliferation | regulation of striated muscle cell differentiation | regulation of ATP metabolic process | regulation of phosphate metabolic process | biomineral tissue development | positive regulation of binding | positive regulation of muscle tissue development | positive regulation of glycoprotein metabolic process | positive regulation of calcineurin-NFAT signaling cascade | positive regulation of intracellular transport | cell activation | positive regulation of MAPK cascade | positive regulation of protein transport | anatomical structure formation involved in morphogenesis | positive regulation of carbohydrate metabolic process | skeletal muscle tissue regeneration | positive regulation of cardiac muscle cell differentiation | bone maturation | positive regulation of protein import into nucleus, translocation | regulation of cell communication | negative regulation of signal transduction | positive regulation of developmental growth | negative regulation of insulin secretion | signaling | positive regulation of growth | response to amyloid-beta | regulation of transcription, DNA-templated | myotube differentiation | myoblast differentiation | cell development | positive regulation of DNA binding | regulation of developmental growth | regulation of T cell proliferation | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | regulation of Ras protein signal transduction | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | positive regulation of MAP kinase activity | positive regulation of protein import into nucleus | regulation of organ growth | regulation of developmental process | developmental process | regulation of muscle cell differentiation | positive regulation of protein import | positive regulation of cell cycle process | regulation of cell growth | cellular protein modification process | carbohydrate derivative metabolic process | regulation of transport | positive regulation of transcription, DNA-templated | regulation of cell-cell adhesion | positive regulation of nucleic acid-templated transcription | positive regulation of heart growth | cochlea development | response to organonitrogen compound | regulation of glycogen biosynthetic process | ERK1 and ERK2 cascade | positive regulation of transcription by RNA polymerase II | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of generation of precursor metabolites and energy | positive regulation of metabolic process | ossification | myoblast proliferation | skeletal system development | cellular metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | positive regulation of cardiac muscle tissue development | regulation of smooth muscle cell proliferation | positive regulation of cell motility | negative regulation of cell death | bone mineralization involved in bone maturation | negative regulation of cell development | positive regulation of insulin-like growth factor receptor signaling pathway | glycoprotein metabolic process | muscle hypertrophy | ear morphogenesis | positive regulation of nucleocytoplasmic transport | tissue regeneration | positive regulation of leukocyte cell-cell adhesion | skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration | negative regulation of cell differentiation | regulation of cellular component organization | muscle system process | positive regulation of signaling | positive regulation of mitotic nuclear division | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | positive regulation of gene expression | regulation of glycogen metabolic process | proteoglycan biosynthetic process | positive regulation of transcription regulatory region DNA binding | regulation of muscle organ development | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

insulin-like growth factor binding protein complex | cell | plasma membrane protein complex | insulin-like growth factor ternary complex | protein-containing complex | plasma membrane | alphav-beta3 integrin-IGF-1-IGF1R complex | extracellular region | extracellular space | cell periphery | intracellular | membrane

PATHWAYS

SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | PID_ER_NONGENOMIC_PATHWAY | PID_SHP2_PATHWAY | PID_IGF1_PATHWAY | PID_CERAMIDE_PATHWAY | PID_AVB3_INTEGRIN_PATHWAY | PID_ECADHERIN_STABILIZATION_PATHWAY | NABA_SECRETED_FACTORS | NABA_MATRISOME_ASSOCIATED | NABA_MATRISOME

PROTEIN FAMILY

Insulin-like | Insulin-like growth factor I | Insulin-like growth factor | Insulin family | Insulin, conserved site | Insulin-like superfamily