QuickView for IGF1R;jsessionid=C77C9914B336A6F5BEBF9CBE7A901665;jsessionid=8569066035447313CA0891258C6832F2 (gene)
- Gene Symbol:
- Igf1r
Mus musculus - Full name:
- insulin-like growth factor I receptor
- Synonyms:
- A330103N21Rik, CD221, D930020L01, IGF-1R, hyft, insulin-like growth factor 1 receptor, IGF-I receptor, line 186
- Genomic Location:
- Chr 7: 75097143-75378553
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Bos taurus , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
| Transcripts Names |
|---|
| NM_010513 |
| XM_006540642 |
| XM_006540645 |
| XM_006540644 |
| XM_006540643 |
| XM_017321986 |
| XM_006540641 |
GO Molecular Function
insulin-like growth factor-activated receptor activity | phosphatidylinositol 3-kinase binding | transmembrane receptor protein tyrosine kinase activity | peptide binding | peptide hormone binding | transmembrane signaling receptor activity | protein-containing complex binding | ribonucleotide binding | insulin binding | nucleotide binding | insulin-like growth factor I binding | signaling receptor binding | carbohydrate derivative binding | growth factor binding | catalytic activity | ATP binding | insulin-like growth factor binding | anion binding | adenyl nucleotide binding | amide binding | signaling receptor activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | hormone binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | insulin receptor binding | transferase activity, transferring phosphorus-containing groups | insulin-activated receptor activity | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | insulin receptor substrate binding | G-protein alpha-subunit binding | heterocyclic compound binding | small molecule binding | protein-hormone receptor activity
GO Biological Process
insulin-like growth factor-activated receptor activity | positive regulation of smooth muscle cell proliferation | response to extracellular stimulus | regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | brain development | cell morphogenesis | positive regulation of hormone biosynthetic process | regulation of cell cycle process | negative regulation of hepatocyte apoptotic process | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | response to nutrient levels | negative regulation of MAPK cascade | cellular response to glucose stimulus | positive regulation of cellular component organization | regulation of neurogenesis | neuron projection morphogenesis | male sex determination | developmental process involved in reproduction | intracellular signal transduction | positive regulation of axon regeneration | regulation of cell development | regulation of localization | morphogenesis of an epithelium | positive regulation of steroid hormone biosynthetic process | regulation of programmed cell death | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | regulation of meiotic cell cycle | regulation of osteoblast proliferation | response to hormone | negative regulation of cellular process | negative regulation of kinase activity | positive regulation of developmental process | regulation of MAP kinase activity | cell differentiation | nervous system development | response to drug | negative regulation of protein phosphorylation | cellular chemical homeostasis | cell part morphogenesis | neurogenesis | glucose homeostasis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | regulation of organelle organization | positive regulation of cellular component movement | generation of neurons | response to antibiotic | positive regulation of cellular biosynthetic process | cellular process | regulation of cell motility | cellular homeostasis | regulation of steroid hormone biosynthetic process | cell projection morphogenesis | negative regulation of signaling | neuron development | reproductive system development | dendritic spine organization | regulation of mitotic nuclear division | multicellular organismal reproductive process | negative regulation of apoptotic process | regulation of cell cycle | response to growth factor | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | positive regulation of cell division | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | regulation of cell differentiation | positive regulation of cytokinesis | regulation of protein kinase B signaling | peptidyl-tyrosine autophosphorylation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of protein complex disassembly | positive regulation of cellular protein metabolic process | epithelium development | cellular response to organonitrogen compound | insulin-like growth factor receptor signaling pathway | establishment of cell polarity | cellular component organization | prostate gland epithelium morphogenesis | response to transforming growth factor beta | regulation of cell division | urogenital system development | head development | response to stimulus | negative regulation of epithelial cell apoptotic process | cell morphogenesis involved in neuron differentiation | positive regulation of cold-induced thermogenesis | metencephalon development | positive regulation of protein metabolic process | positive regulation of phosphatidylinositol 3-kinase signaling | gland morphogenesis | negative regulation of protein kinase activity | regulation of cell proliferation | positive regulation of lipid biosynthetic process | ovulation cycle | response to peptide | response to glucose | response to L-glutamate | phosphatidylinositol-mediated signaling | reproduction | response to alcohol | rhythmic process | regulation of neuron projection regeneration | positive regulation of meiotic cell cycle | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | protein modification process | regulation of steroid biosynthetic process | macromolecule modification | regulation of steroid metabolic process | response to ethanol | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | response to nitrogen compound | cellular response to hormone stimulus | system development | positive regulation of response to wounding | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of organelle organization | negative regulation of phosphate metabolic process | positive regulation of neuron projection development | multicellular organism development | negative regulation of catalytic activity | cellular glucose homeostasis | cellular response to peptide hormone stimulus | regulation of MAPK cascade | phosphorus metabolic process | response to amino acid | mammary gland development | protein complex oligomerization | cellular response to insulin stimulus | positive regulation of protein kinase B signaling | regulation of catalytic activity | cerebellum development | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of hormone levels | positive regulation of neuron projection regeneration | regulation of protein complex disassembly | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of neuron differentiation | regulation of gene expression | pancreas development | axon development | cellular response to peptide | exocrine pancreas development | insulin receptor signaling pathway | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | amyloid-beta clearance | positive regulation of cell projection organization | negative regulation of DNA-binding transcription factor activity | positive regulation of intracellular signal transduction | regulation of cellular component movement | response to nutrient | synapse organization | axonogenesis | positive regulation of cell differentiation | positive regulation of steroid metabolic process | positive regulation of cell migration | negative regulation of protein kinase B signaling | regulation of hormone metabolic process | regulation of cellular protein metabolic process | hindbrain development | phosphorylation | sex determination | inositol lipid-mediated signaling | protein tetramerization | epidermis development | response to toxic substance | endocrine system development | regulation of epithelial cell apoptotic process | protein phosphorylation | cell morphogenesis involved in differentiation | establishment or maintenance of cell polarity | phosphate-containing compound metabolic process | cellular response to angiotensin | regulation of muscle cell apoptotic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of cytokinesis | cellular response to amyloid-beta | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of osteoblast proliferation | homeostatic process | positive regulation of cell proliferation | response to monosaccharide | inactivation of MAPKK activity | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | regulation of lipid biosynthetic process | negative regulation of cholangiocyte apoptotic process | regulation of mitotic cell cycle | protein tyrosine kinase activity | cellular response to transforming growth factor beta stimulus | response to angiotensin | neuron differentiation | multicellular organism reproduction | protein-containing complex assembly | protein metabolic process | cellular response to insulin-like growth factor stimulus | positive regulation of protein modification process | response to organic substance | gland development | tissue morphogenesis | digestive system development | regulation of kinase activity | positive regulation of steroid biosynthetic process | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | response to insulin | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | cellular component maintenance | cell projection organization | metabolic process | positive regulation of cell development | insulin-activated receptor activity | regulation of RNA biosynthetic process | negative regulation of programmed cell death | adrenal gland development | cellular response to carbohydrate stimulus | negative regulation of muscle cell apoptotic process | chemical homeostasis | immune response | protein kinase activity | neuron projection development | organic substance metabolic process | animal organ development | negative regulation of cellular protein metabolic process | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | prostate gland morphogenesis | regulation of JNK cascade | positive regulation of MAPK cascade | regulation of axon regeneration | negative regulation of protein metabolic process | estrous cycle | regulation of response to wounding | regulation of stress-activated MAPK cascade | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | response to amyloid-beta | regulation of transcription, DNA-templated | cell development | dendritic spine maintenance | positive regulation of phosphorylation | cellular protein metabolic process | protein heterooligomerization | anatomical structure morphogenesis | prostate gland development | reproductive structure development | regulation of nervous system development | regulation of developmental process | positive regulation of DNA metabolic process | kinase activity | developmental process | positive regulation of cell cycle process | cellular protein modification process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of neuron differentiation | positive regulation of lipid metabolic process | regulation of cell projection organization | immune system process | cellular metabolic process | cellular response to organic substance | exocrine system development | regulation of cell death | regulation of smooth muscle cell proliferation | positive regulation of cell motility | response to carbohydrate | negative regulation of cell death | carbohydrate homeostasis | regulation of cellular component organization | positive regulation of signaling | positive regulation of mitotic nuclear division | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | positive regulation of gene expression | regulation of hormone biosynthetic process | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | sarcolemma | catalytic complex | neuron projection | somatodendritic compartment | cell body | protein kinase complex | cell | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | intracellular organelle | receptor complex | membrane microdomain | protein-containing complex | cell projection | plasma membrane | membrane raft | transferase complex | alphav-beta3 integrin-IGF-1-IGF1R complex | integral component of plasma membrane | T-tubule | membrane-bounded organelle | nucleus | organelle | insulin receptor complex | cell periphery | axon | plasma membrane raft | intracellular | caveola | membrane | intrinsic component of plasma membrane
