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QuickView for IL10;jsessionid=95BC35DA8803D047E90DC79134FA0CF1;jsessionid=023C5288FF3F6B36D4DE9B6A251EC73B (gene)


Gene Symbol:
Il10 Rattus norvegicus Rattus norvegicus
Full name:
interleukin 10
Synonyms:
IL10X, interleukin-10, CSIF, IL-10, cytokine synthesis inhibitory factor
Genomic Location:
Chr 13: 43953859-43958332
Description:
factor involved in the inhibition of cytokine synthesis
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Canis lupus familiaris Gallus gallus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_012854
XM_008769426
XM_006249712
Protein Names
P29456
Q63263



GO Molecular Function

signaling receptor binding | interleukin-10 receptor binding | cytokine receptor binding | molecular function regulator | protein binding | receptor regulator activity | receptor ligand activity | cytokine activity | growth factor receptor binding

GO Biological Process

negative regulation of leukocyte activation | negative regulation of membrane protein ectodomain proteolysis | regulation of hydrogen peroxide-induced cell death | positive regulation of macromolecule biosynthetic process | negative regulation of immune system process | regulation of cellular response to oxidative stress | regulation of response to oxidative stress | regulation of B cell activation | response to lipopolysaccharide | developmental process involved in reproduction | negative regulation of peptide secretion | regulation of myeloid dendritic cell activation | positive regulation of apoptotic process | regulation of localization | morphogenesis of an epithelium | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | negative regulation of cellular response to oxidative stress | defense response to other organism | regulation of immune system process | response to hormone | regulation of nitric oxide biosynthetic process | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | positive regulation of epithelial cell proliferation | negative regulation of growth of symbiont involved in interaction with host | defense response | negative regulation of B cell proliferation | response to drug | regulation of sprouting angiogenesis | negative regulation of protein secretion | positive regulation of endothelial cell proliferation | negative regulation of chronic inflammatory response | positive regulation of protein secretion | negative regulation of proteolysis | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | regulation of cytokine activity | negative regulation of inflammatory response | negative regulation of oxidative stress-induced neuron death | regulation of cytokine biosynthetic process | reproductive system development | response to estradiol | positive regulation of macrophage activation | regulation of embryonic development | cellular response to hepatocyte growth factor stimulus | negative regulation of apoptotic process | negative regulation of secretion | regulation of proteolysis | regulation of cell cycle | response to growth factor | positive regulation of nitrogen compound metabolic process | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | regulation of binding | regulation of neurological system process | regulation of lymphocyte apoptotic process | regeneration | regulation of angiogenesis | regulation of immune response | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | labyrinthine layer morphogenesis | regulation of metabolic process | negative regulation of cytokine secretion | hepaticobiliary system development | negative regulation of mononuclear cell proliferation | cellular response to molecule of bacterial origin | negative regulation of tumor necrosis factor production | negative regulation of oxidative stress-induced cell death | epithelium development | negative regulation of receptor binding | negative regulation of response to drug | regulation of peptide secretion | regulation of vasculature development | response to stimulus | negative regulation of epithelial cell apoptotic process | negative regulation of protein transport | positive regulation of immune system process | negative regulation of cell adhesion | negative regulation of neurological system process | response to stress | regulation of heterotypic cell-cell adhesion | negative regulation of tumor necrosis factor superfamily cytokine production | negative regulation of lymphocyte activation | regulation of response to drug | regulation of cell proliferation | negative regulation of interferon-gamma production | branching involved in labyrinthine layer morphogenesis | response to peptide | positive regulation of cell activation | reproduction | positive regulation of cytokine secretion | positive regulation of sprouting angiogenesis | response to molecule of bacterial origin | negative regulation of transport | cellular response to organic cyclic compound | regulation of protein transport | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | regulation of synapse structure or activity | negative regulation of nitric oxide biosynthetic process | regulation of peptide transport | regulation of cell adhesion | embryo development | negative regulation of reactive oxygen species biosynthetic process | molecular function regulator | embryonic placenta development | receptor biosynthetic process | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | regulation of cellular response to stress | regulation of neurotransmitter levels | response to nitrogen compound | cellular response to hormone stimulus | response to inactivity | response to external biotic stimulus | system development | reproductive process | regulation of signal transduction | negative regulation of secretion by cell | negative regulation of growth | negative regulation of interleukin-6 production | multicellular organism development | response to activity | regulation of sensory perception of pain | positive regulation of cell cycle | regulation of gene expression | positive regulation of secretion | response to lipid | negative regulation of hydrogen peroxide-induced cell death | negative regulation of cytokine production | response to carbon monoxide | positive regulation of cellular metabolic process | regulation of lymphocyte activation | negative regulation of smooth muscle cell proliferation | liver development | regulation of synapse organization | regulation of nitrogen compound metabolic process | response to corticosteroid | regulation of transcription by RNA polymerase II | regulation of endothelial cell apoptotic process | negative regulation of binding | negative regulation of heterotypic cell-cell adhesion | negative regulation of interleukin-12 production | biosynthetic process | labyrinthine layer development | regulation of cellular protein metabolic process | negative regulation of immune response | positive regulation of B cell apoptotic process | regulation of complement-dependent cytotoxicity | response to toxic substance | positive regulation of leukocyte apoptotic process | regulation of epithelial cell apoptotic process | regulation of tumor necrosis factor production | negative regulation of hydrogen peroxide-induced neuron death | defense response to protozoan | regulation of B cell apoptotic process | negative regulation of cytokine biosynthetic process | response to hepatocyte growth factor | regulation of macrophage activation | regulation of cellular response to drug | negative regulation of cytokine activity | response to bacterium | negative regulation of cell-cell adhesion | chordate embryonic development | negative regulation of protein binding | regulation of cellular metabolic process | liver regeneration | negative regulation of cell activation | inflammatory response | regulation of cytokine production involved in immune response | regulation of protein metabolic process | defense response to bacterium | positive regulation of cell proliferation | positive regulation of establishment of protein localization | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | negative regulation of vascular smooth muscle cell proliferation | positive regulation of transport | embryonic morphogenesis | negative regulation of B cell activation | positive regulation of molecular function | regulation of cytokine secretion | regulation of signaling receptor activity | receptor regulator activity | regulation of establishment of protein localization | positive regulation of MHC class II biosynthetic process | regulation of growth | response to organic substance | gland development | tissue morphogenesis | regulation of response to reactive oxygen species | regulation of DNA-binding transcription factor activity | response to insulin | anatomical structure development | regulation of chronic inflammatory response | metabolic process | negative regulation of response to oxidative stress | negative regulation of growth of symbiont in host | regulation of protein catabolic process | negative regulation of tumor necrosis factor biosynthetic process | negative regulation of leukocyte proliferation | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | negative regulation of programmed cell death | embryonic organ development | regulation of cytokine secretion involved in immune response | regulation of cell-cell adhesion involved in gastrulation | regulation of secretion | positive regulation of cell death | negative regulation of sensory perception of pain | receptor ligand activity | immune response | cytokine activity | organic substance metabolic process | regulation of tumor necrosis factor biosynthetic process | negative regulation of biosynthetic process | animal organ development | regulation of endothelial cell proliferation | negative regulation of cellular protein metabolic process | regulation of cell activation | regulation of protein secretion | positive regulation of programmed cell death | response to protozoan | positive regulation of cytokine production | positive regulation of lymphocyte apoptotic process | morphogenesis of a branching epithelium | positive regulation of protein transport | regulation of reactive oxygen species biosynthetic process | negative regulation of protein catabolic process | negative regulation of protein metabolic process | cellular response to estradiol stimulus | regulation of response to wounding | regulation of cell communication | negative regulation of molecular function | regulation of transcription, DNA-templated | regulation of protein binding | response to organic cyclic compound | regulation of epithelial cell proliferation | regulation of cytokine production | morphogenesis of a branching structure | anatomical structure morphogenesis | response to biotic stimulus | reproductive structure development | regulation of developmental process | developmental process | negative regulation of cytokine secretion involved in immune response | regulation of gastrulation | regulation of transport | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | regulation of B cell proliferation | negative regulation of cell proliferation | regulation of cell-cell adhesion | negative regulation of chronic inflammatory response to antigenic stimulus | receptor metabolic process | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | embryonic placenta morphogenesis | positive regulation of transcription by RNA polymerase II | in utero embryonic development | positive regulation of metabolic process | negative regulation of myeloid dendritic cell activation | regulation of interferon-gamma production | negative regulation of lymphocyte proliferation | immune system process | cellular metabolic process | placenta development | cellular response to organic substance | regulation of protein localization | regulation of cell death | regulation of smooth muscle cell proliferation | response to steroid hormone | negative regulation of inflammatory response to antigenic stimulus | negative regulation of cell death | regulation of interleukin-6 production | regulation of inflammatory response | aging | positive regulation of angiogenesis | regulation of cellular component organization | response to other organism | negative regulation of reactive oxygen species metabolic process | regulation of signaling | negative regulation of endothelial cell apoptotic process | animal organ regeneration | positive regulation of gene expression | response to glucocorticoid | cellular response to growth factor stimulus | cellular response to lipopolysaccharide | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

extracellular region | extracellular space