QuickView for IL6;jsessionid=5E2DA6E31B18647F822F546D0FBFA7EE;jsessionid=339BED8AF0DF67A81BAF6F3AE4DE1D6F (gene)
- Gene Symbol:
- IL6
Bos taurus - Full name:
- interleukin 6 (interferon, beta 2)
- Synonyms:
- N/A
- Genomic Location:
- Chr 4: 32756555-32760923
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
NFE2_01 , IRF1_01 , IK1_01 , OCT1_05 , AP1FJ_Q2 , AP1_Q2 , AP1_Q4 , CCANNAGRKGGC_UNKNOWN , TCF11MAFG_01 , GATA1_05
GO Molecular Function
signaling receptor binding | cytokine receptor binding | molecular function regulator | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | cytokine activity | growth factor receptor binding | interleukin-6 receptor binding
GO Biological Process
leukocyte homeostasis | positive regulation of smooth muscle cell proliferation | adaptive immune response | positive regulation of macromolecule biosynthetic process | response to virus | CD4-positive, alpha-beta T cell differentiation | response to cytokine | regulation of B cell activation | CD4-positive, alpha-beta T cell activation | response to lipopolysaccharide | interleukin-6-mediated signaling pathway | positive regulation of apoptotic process | regulation of localization | negative regulation of collagen biosynthetic process | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | T cell lineage commitment | defense response to other organism | regulation of immune system process | response to hormone | neutrophil homeostasis | negative regulation of cellular process | positive regulation of lymphocyte activation | T-helper cell lineage commitment | cell differentiation | defense response | nervous system development | response to drug | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | generation of neurons | positive regulation of protein secretion | response to antibiotic | positive regulation of cellular biosynthetic process | regulation of immunoglobulin secretion | cellular process | lymphocyte differentiation | T-helper 17 cell differentiation | positive regulation of immune effector process | positive regulation of peptidyl-serine phosphorylation | neuron development | immune system development | negative regulation of apoptotic process | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment | response to inorganic substance | response to hydrogen peroxide | regulation of cellular process | leukocyte activation | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | T cell differentiation involved in immune response | cellular response to molecule of bacterial origin | positive regulation of translation | positive regulation of cellular protein metabolic process | cellular component organization | T cell activation | inflammatory cell apoptotic process | regulation of peptide secretion | response to stimulus | alpha-beta T cell activation involved in immune response | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of immunoglobulin production | response to stress | positive regulation of JAK-STAT cascade | leukocyte activation involved in immune response | positive regulation of lymphocyte proliferation | posttranscriptional regulation of gene expression | regulation of cell proliferation | T-helper 17 cell lineage commitment | positive regulation of cell-cell adhesion | programmed cell death | positive regulation of cell activation | response to molecule of bacterial origin | cellular response to toxic substance | positive regulation of T cell activation | regulation of protein transport | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | regulation of peptide transport | regulation of cell adhesion | molecular function regulator | myeloid cell homeostasis | regulation of nucleic acid-templated transcription | T-helper cell differentiation | positive regulation of peptide secretion | leukocyte differentiation | apoptotic process | cellular response to interleukin-6 | positive regulation of mononuclear cell proliferation | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | response to external biotic stimulus | system development | regulation of signal transduction | cellular response to antibiotic | multicellular organism development | regulation of MAPK cascade | regulation of collagen biosynthetic process | positive regulation of inflammatory response | cellular response to oxidative stress | regulation of phosphorylation | regulation of acute inflammatory response | regulation of T cell activation | regulation of gene expression | positive regulation of secretion | cellular response to stress | response to lipid | alpha-beta T cell lineage commitment | positive regulation of cellular metabolic process | defense response to virus | positive regulation of protein phosphorylation | regulation of lymphocyte activation | regulation of nitrogen compound metabolic process | positive regulation of STAT cascade | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | response to corticosteroid | regulation of transcription by RNA polymerase II | alpha-beta T cell differentiation | response to oxidative stress | acute-phase response | homeostasis of number of cells | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | positive regulation of T cell proliferation | T cell activation involved in immune response | positive regulation of chemokine production | response to toxic substance | cellular response to drug | response to bacterium | cell communication | regulation of cellular metabolic process | positive regulation of tyrosine phosphorylation of STAT protein | inflammatory response | cell activation involved in immune response | regulation of collagen metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of B cell activation | positive regulation of transport | lymphocyte activation | positive regulation of molecular function | neuron differentiation | hepatic immune response | T cell differentiation | regulation of signaling receptor activity | receptor regulator activity | regulation of establishment of protein localization | positive regulation of protein modification process | T cell selection | response to organic substance | regulation of JAK-STAT cascade | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | growth factor activity | cell projection organization | cell fate commitment | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | negative regulation of programmed cell death | positive T cell selection | cellular response to hydrogen peroxide | regulation of secretion | positive regulation of cell death | receptor ligand activity | positive regulation of interleukin-6 production | immune response | cellular response to reactive oxygen species | neuron projection development | cytokine activity | neutrophil apoptotic process | positive regulation of acute inflammatory response | cell death | negative regulation of biosynthetic process | animal organ development | response to reactive oxygen species | regulation of cell activation | regulation of protein secretion | positive regulation of programmed cell death | alpha-beta T cell activation | regulation of phosphate metabolic process | positive regulation of cytokine production | cell activation | positive regulation of MAPK cascade | positive regulation of protein transport | regulation of peptidyl-serine phosphorylation | regulation of cell communication | signaling | regulation of immunoglobulin production | regulation of transcription, DNA-templated | response to organic cyclic compound | cell development | regulation of T cell proliferation | positive regulation of phosphorylation | regulation of cytokine production | response to biotic stimulus | positive regulation of immunoglobulin secretion | developmental process | regulation of chemokine production | myeloid cell apoptotic process | regulation of transport | positive regulation of transcription, DNA-templated | regulation of cell-cell adhesion | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | regulation of vascular endothelial growth factor production | positive regulation of metabolic process | acute inflammatory response | immune system process | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of protein localization | regulation of cell death | regulation of smooth muscle cell proliferation | response to steroid hormone | regulation of translation | response to interleukin-6 | negative regulation of cell death | regulation of interleukin-6 production | regulation of inflammatory response | positive regulation of leukocyte cell-cell adhesion | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | response to glucocorticoid | cellular response to lipopolysaccharide | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | cell | plasma membrane protein complex | intrinsic component of membrane | receptor complex | protein-containing complex | plasma membrane | integral component of plasma membrane | extracellular region | interleukin-6 receptor complex | extracellular space | cell periphery | membrane | intrinsic component of plasma membrane
