QuickView for IL6ST;jsessionid=D61C2B4F1394EB18C9E9AB1F0B93EA30;jsessionid=657A5B931D3C23AD79A29FBC32213DE4;jsessionid=C588027B7C23A4F37AAE55B17B8BF33F (gene)
- Gene Symbol:
- Il6st
Rattus norvegicus - Full name:
- interleukin 6 signal transducer
- Synonyms:
- Ac1055, Gp130, Il-6rb, interleukin-6 receptor subunit beta, IL-6 receptor subunit beta, IL-6R subunit beta, membrane glycoprotein 130, oncostatin-M receptor subunit alpha
- Genomic Location:
- Chr 2: 43806301-43842364
- Description:
-
IL-6 signal transducing molecule
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
cytokine binding | oncostatin-M receptor activity | transmembrane signaling receptor activity | signaling receptor binding | ciliary neurotrophic factor receptor activity | cytokine receptor binding | growth factor binding | leukemia inhibitory factor receptor activity | signaling receptor activity | ciliary neurotrophic factor receptor binding | cytokine receptor activity | interleukin-11 binding | protein binding | interleukin-6 receptor activity | interleukin-6 binding | interleukin-11 receptor activity | growth factor receptor binding | interleukin-6 receptor binding
GO Biological Process
response to extracellular stimulus | positive regulation of locomotion | response to nutrient levels | response to cytokine | regulation of neurogenesis | interleukin-6-mediated signaling pathway | regulation of cell development | regulation of localization | positive regulation of peptidyl-tyrosine phosphorylation | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | positive regulation of lymphocyte activation | cell differentiation | nervous system development | generation of precursor metabolites and energy | cellular chemical homeostasis | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | generation of neurons | oncostatin-M-mediated signaling pathway | ciliary neurotrophic factor-mediated signaling pathway | cellular process | oncostatin-M receptor activity | regulation of cell motility | cellular homeostasis | negative regulation of signaling | triglyceride metabolic process | leukemia inhibitory factor signaling pathway | regulation of response to cytokine stimulus | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | regulation of cell differentiation | regulation of cellular process | regulation of osteoblast differentiation | regulation of metabolic process | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | cellular lipid metabolic process | calcium ion homeostasis | response to stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of JAK-STAT cascade | cellular polysaccharide metabolic process | positive regulation of lymphocyte proliferation | regulation of cell proliferation | ciliary neurotrophic factor receptor activity | polysaccharide metabolic process | positive regulation of cell-cell adhesion | regulation of smooth muscle cell migration | positive regulation of cell activation | positive regulation of T cell activation | positive regulation of gliogenesis | regulation of cell adhesion | metal ion homeostasis | negative regulation of interleukin-6-mediated signaling pathway | cellular response to interleukin-6 | positive regulation of mononuclear cell proliferation | system development | leukemia inhibitory factor receptor activity | glycogen metabolic process | regulation of signal transduction | multicellular organism development | positive regulation of smooth muscle cell migration | lipid metabolic process | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | regulation of ossification | regulation of T cell activation | triglyceride mobilization | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | cellular ion homeostasis | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of Notch signaling pathway | enzyme linked receptor protein signaling pathway | cellular carbohydrate metabolic process | positive regulation of STAT cascade | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | regulation of cellular component movement | response to nutrient | positive regulation of cell differentiation | positive regulation of cell migration | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | positive regulation of T cell proliferation | positive regulation of ossification | carbohydrate metabolic process | cation homeostasis | cytokine receptor activity | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | positive regulation of tyrosine phosphorylation of STAT protein | regulation of protein metabolic process | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of cytokine-mediated signaling pathway | regulation of locomotion | glycerolipid metabolic process | positive regulation of osteoblast differentiation | positive regulation of protein modification process | response to organic substance | neutral lipid metabolic process | regulation of JAK-STAT cascade | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | negative regulation of response to cytokine stimulus | metabolic process | positive regulation of cell development | positive regulation of leukocyte activation | oxidation-reduction process | interleukin-6 receptor activity | positive regulation of glial cell differentiation | chemical homeostasis | regulation of secretion | organic substance metabolic process | regulation of cell activation | ion homeostasis | regulation of phosphate metabolic process | positive regulation of astrocyte differentiation | interleukin-11-mediated signaling pathway | interleukin-27-mediated signaling pathway | regulation of glial cell differentiation | regulation of cell communication | regulation of gliogenesis | negative regulation of signal transduction | signaling | energy reserve metabolic process | regulation of T cell proliferation | positive regulation of phosphorylation | interleukin-11 receptor activity | regulation of nervous system development | negative regulation of cytosolic calcium ion concentration | regulation of developmental process | energy derivation by oxidation of organic compounds | developmental process | cellular glucan metabolic process | regulation of transport | regulation of cell-cell adhesion | cellular metal ion homeostasis | negative regulation of cytokine-mediated signaling pathway | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | regulation of astrocyte differentiation | positive regulation of cell motility | response to interleukin-6 | acylglycerol metabolic process | divalent inorganic cation homeostasis | positive regulation of leukocyte cell-cell adhesion | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | dendrite | ciliary neurotrophic factor receptor complex | neuron projection | oncostatin-M receptor complex | somatodendritic compartment | cell body | cell | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | external side of plasma membrane | receptor complex | dendritic tree | protein-containing complex | cell projection | plasma membrane | neuronal cell body membrane | integral component of plasma membrane | extracellular region | interleukin-6 receptor complex | extracellular space | cell periphery | cell body membrane | cell surface | membrane | intrinsic component of plasma membrane
