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QuickView for IQGAP1;jsessionid=8F8CC4D44A33DDC3954C480040676C78;jsessionid=90EB784004352C194A911215DBF23FC4 (gene)


Gene Symbol:
Iqgap1 Rattus norvegicus Rattus norvegicus
Full name:
IQ motif containing GTPase activating protein 1
Synonyms:
ras GTPase-activating-like protein IQGAP1
Genomic Location:
Chr 1: 136551192-136707733
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
XM_341877
XM_001066654
NM_001108489
Protein Names
G3V7Q7



GO Molecular Function

protein kinase activator activity | protein serine/threonine kinase activator activity | kinase binding | enzyme activator activity | protein kinase regulator activity | GTPase binding | Rho GTPase binding | S100 protein binding | kinase regulator activity | protein kinase binding | enzyme binding | mitogen-activated protein kinase binding | protein-containing complex binding | lipid binding | phospholipid binding | Ras GTPase binding | molecular function regulator | protein domain specific binding | anion binding | ion binding | phosphatidylinositol-3,4,5-trisphosphate binding | protein binding | protein phosphatase binding | kinase activator activity | Rac GTPase binding | phosphatidylinositol binding | small GTPase binding | enzyme regulator activity | calmodulin binding | phosphatase binding | phosphatidylinositol phosphate binding

GO Biological Process

cell morphogenesis | protein kinase activator activity | positive regulation of locomotion | regulation of dephosphorylation | protein serine/threonine kinase activator activity | positive regulation of cellular component organization | regulation of neurogenesis | neuron projection morphogenesis | positive regulation of adherens junction organization | regulation of cellular localization | enzyme activator activity | cellular response to platelet-derived growth factor stimulus | regulation of cell development | regulation of localization | protein kinase regulator activity | positive regulation of peptidyl-tyrosine phosphorylation | response to hormone | negative regulation of cellular process | positive regulation of developmental process | regulation of MAP kinase activity | response to metal ion | cell differentiation | nervous system development | cell part morphogenesis | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | generation of neurons | neuron projection extension | cellular process | regulation of cell motility | cell projection morphogenesis | developmental growth | neuron development | kinase regulator activity | positive regulation of protein kinase activity | regulation of cell cycle | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | response to inorganic substance | negative regulation of cellular metabolic process | response to peptide hormone | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | epidermal growth factor receptor signaling pathway | positive regulation of cellular protein metabolic process | cellular component organization | cellular response to metal ion | response to stimulus | regulation of cellular protein localization | cellular response to fibroblast growth factor stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | positive regulation of cellular protein localization | response to peptide | regulation of smooth muscle cell migration | cellular response to inorganic substance | ERBB signaling pathway | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | regulation of cell adhesion | activation of protein kinase activity | positive regulation of cell-matrix adhesion | molecular function regulator | positive regulation of vascular associated smooth muscle cell migration | response to nitrogen compound | positive regulation of cell junction assembly | system development | regulation of signal transduction | negative regulation of phosphate metabolic process | positive regulation of neuron projection development | regulation of adherens junction organization | multicellular organism development | regulation of MAPK cascade | positive regulation of smooth muscle cell migration | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | fibroblast growth factor receptor signaling pathway | regulation of neuron differentiation | platelet-derived growth factor receptor signaling pathway | regulation of protein autophosphorylation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cell-substrate adhesion | enzyme linked receptor protein signaling pathway | positive regulation of cell projection organization | positive regulation of intracellular signal transduction | regulation of cellular component movement | positive regulation of cell differentiation | response to platelet-derived growth factor | positive regulation of cell migration | regulation of cellular protein metabolic process | regulation of GTPase activity | positive regulation of peptidyl-tyrosine autophosphorylation | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | regulation of locomotion | positive regulation of dendrite development | regulation of mitotic cell cycle | positive regulation of molecular function | cellular response to epidermal growth factor stimulus | response to angiotensin | neuron differentiation | positive regulation of focal adhesion assembly | positive regulation of protein modification process | cellular response to calcium ion | response to organic substance | regulation of kinase activity | regulation of intracellular signal transduction | regulation of focal adhesion assembly | anatomical structure development | developmental growth involved in morphogenesis | kinase activator activity | cell surface receptor signaling pathway | positive regulation of neurogenesis | cell projection organization | positive regulation of cell development | neuron projection development | positive regulation of cellular component biogenesis | positive regulation of cell-substrate adhesion | positive regulation of kinase activity | regulation of phosphate metabolic process | positive regulation of MAPK cascade | response to epidermal growth factor | regulation of dendrite development | regulation of cell communication | signaling | cell development | positive regulation of phosphorylation | enzyme regulator activity | regulation of cytokine production | anatomical structure morphogenesis | positive regulation of MAP kinase activity | regulation of nervous system development | regulation of developmental process | developmental process | positive regulation of protein autophosphorylation | regulation of cell junction assembly | developmental cell growth | response to fibroblast growth factor | response to organonitrogen compound | negative regulation of dephosphorylation | response to calcium ion | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | positive regulation of neuron differentiation | regulation of cell projection organization | cellular response to organic substance | regulation of protein localization | positive regulation of cell motility | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | regulation of cell-matrix adhesion | cellular response to growth factor stimulus | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

supramolecular fiber | exocytic vesicle | cytoplasmic side of plasma membrane | intracellular membrane-bounded organelle | neuron projection | extrinsic component of membrane | ruffle | adherens junction | focal adhesion | cytoplasmic vesicle | cell | cytoplasmic side of membrane | extrinsic component of plasma membrane | distal axon | ribonucleoprotein granule | microtubule | cytoplasm | cell-substrate junction | intracellular organelle | actin cytoskeleton | membrane microdomain | cell-cell junction | protein-containing complex | cell projection | secretory vesicle | endomembrane system | plasma membrane | extrinsic component of cytoplasmic side of plasma membrane | midbody | cell leading edge | membrane raft | ribonucleoprotein complex | vesicle | transport vesicle | microtubule cytoskeleton | site of polarized growth | membrane-bounded organelle | nucleus | organelle | cytoplasmic ribonucleoprotein granule | cell periphery | axon | cell-substrate adherens junction | growth cone | intracellular vesicle | cytoskeleton | intracellular | cell junction | lateral plasma membrane | membrane | supramolecular complex