QuickView for IRF5;jsessionid=82A0F8D7E969DB1DD438A19E3B9A9930;jsessionid=A0EBF7DEBBF675DF3B2E13C2D661EF1B;jsessionid=593CA0EDBCDC20F341C68BFB29A58835;jsessionid=A5CB29CE563F7563605C4C3896B9AAF9 (gene)

Gene Symbol:

IRF5 Homo sapiens

Full name:

interferon regulatory factor 5

Synonyms:

SLEB10, interferon regulatory factor 5

Genomic Location:

Chr 7: 128365230-128377325

Description:

This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding ...

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This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CEBPB_01

Cytogenetic Map:

7q32.1

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