Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for IRG1;jsessionid=18E379E3AF9C24BCF76B02F316E6DA58 (gene)


Gene Symbol:
ACOD1 Homo sapiens Homo sapiens
Full name:
aconitate decarboxylase 1
Synonyms:
CAD, IRG1, cis-aconitate decarboxylase, cis-aconitic acid decarboxylase, immune-responsive gene 1 protein homolog, immunoresponsive 1 homolog
Genomic Location:
Chr 13: 76409986-76452604
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Cytogenetic Map:
chr 13
13q22.3


Protein Names
A6NK06



GO Molecular Function

hydro-lyase activity | lyase activity | carbon-carbon lyase activity | catalytic activity | aconitate decarboxylase activity | carboxy-lyase activity | 2-methylcitrate dehydratase activity

GO Biological Process

positive regulation of immune response | negative regulation of immune system process | response to cytokine | response to interleukin-1 | response to lipopolysaccharide | negative regulation of type I interferon production | cellular response to progesterone stimulus | regulation of immune system process | response to hormone | negative regulation of cellular process | propionate metabolic process, methylcitrate cycle | cellular response to tumor necrosis factor | positive regulation of antimicrobial humoral response | defense response | tolerance induction to lipopolysaccharide | response to drug | negative regulation of toll-like receptor 4 signaling pathway | regulation of toll-like receptor 4 signaling pathway | cellular process | negative regulation of inflammatory response | negative regulation of signaling | short-chain fatty acid metabolic process | positive regulation of reactive oxygen species metabolic process | response to progesterone | female pregnancy | tolerance induction | immune system development | negative regulation of innate immune response | regulation of immune response | regulation of cellular process | cellular response to lipid | regulation of metabolic process | cellular response to molecule of bacterial origin | cellular lipid metabolic process | negative regulation of toll-like receptor signaling pathway | cellular response to interferon-gamma | regulation of type I interferon production | response to stimulus | monocarboxylic acid metabolic process | positive regulation of immune system process | response to stress | regulation of antimicrobial humoral response | response to interferon-beta | regulation of humoral immune response | reproduction | response to molecule of bacterial origin | cellular response to organic cyclic compound | negative regulation of toll-like receptor 2 signaling pathway | regulation of nucleic acid-templated transcription | negative regulation of NF-kappaB transcription factor activity | cellular response to hormone stimulus | response to external biotic stimulus | system development | reproductive process | regulation of signal transduction | multicellular organism development | regulation of toll-like receptor signaling pathway | antibiotic metabolic process | lipid metabolic process | regulation of gene expression | propionate metabolic process | response to ketone | response to lipid | negative regulation of cytokine production | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | negative regulation of DNA-binding transcription factor activity | positive regulation of humoral immune response | cellular response to cytokine stimulus | negative regulation of immune response | cellular response to drug | response to bacterium | regulation of cellular metabolic process | inflammatory response | regulation of RNA metabolic process | drug metabolic process | carboxylic acid metabolic process | response to organic substance | regulation of innate immune response | regulation of lipopolysaccharide-mediated signaling pathway | regulation of DNA-binding transcription factor activity | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | immune response | organic substance metabolic process | cellular response to steroid hormone stimulus | fatty acid metabolic process | response to interferon-gamma | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | regulation of transcription, DNA-templated | response to organic cyclic compound | organic acid metabolic process | regulation of cytokine production | cellular response to interferon-beta | response to biotic stimulus | developmental process | cellular response to interleukin-1 | regulation of reactive oxygen species metabolic process | innate immune response | embryo implantation | positive regulation of metabolic process | immune system process | cellular metabolic process | negative regulation of lipopolysaccharide-mediated signaling pathway | response to tumor necrosis factor | cellular response to organic substance | response to steroid hormone | regulation of inflammatory response | response to other organism | regulation of signaling | cellular response to lipopolysaccharide | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | intracellular