QuickView for IRS2;jsessionid=E16D36383CAB3AA47521EFD6C423D574;jsessionid=7CB0D76A97024CD4A63FD9CD5F0FD06A;jsessionid=384C705533FA1DF3B5B8358BF161639B;jsessionid=AF19E8FA19099E7267CFC1B8D7D5063B (gene)
- Gene Symbol:
- Irs2
Mus musculus - Full name:
- insulin receptor substrate 2
- Synonyms:
- Irs-2, insulin receptor substrate 2, 4PS
- Genomic Location:
- Chr 8: 10986961-11008430
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for let-7 , Predicted Gene Targets for miR-129 , Predicted Gene Targets for miR-135 , Predicted Gene Targets for miR-153 , Predicted Gene Targets for miR-181 , Predicted Gene Targets for miR-141 , Predicted Gene Targets for miR-208 , Predicted Gene Targets for miR-224 , Predicted Gene Targets for miR-25 , Predicted Gene Targets for miR-30
GO Molecular Function
phosphatidylinositol 3-kinase binding | kinase binding | 14-3-3 protein binding | protein kinase binding | enzyme binding | protein-containing complex binding | signaling receptor binding | protein domain specific binding | protein binding | insulin receptor binding | protein phosphatase binding | phosphatase binding
GO Biological Process
negative regulation of phosphorylation | brain development | positive regulation of glycogen biosynthetic process | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | regulation of B cell activation | regulation of localization | regulation of carbohydrate metabolic process | regulation of programmed cell death | positive regulation of lipid catabolic process | regulation of immune system process | response to hormone | negative regulation of cellular process | negative regulation of kinase activity | positive regulation of fatty acid oxidation | positive regulation of lymphocyte activation | nervous system development | positive regulation of cellular component movement | regulation of peptide hormone secretion | positive regulation of protein secretion | regulation of lipid transport | positive regulation of cellular biosynthetic process | cellular process | regulation of glucose import | regulation of cell motility | negative regulation of apoptotic process | negative regulation of cellular metabolic process | response to peptide hormone | regulation of lymphocyte apoptotic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | cellular response to organonitrogen compound | head development | regulation of peptide secretion | response to stimulus | regulation of insulin secretion | positive regulation of immune system process | positive regulation of lymphocyte proliferation | regulation of cell proliferation | response to peptide | positive regulation of glucose import | positive regulation of B cell proliferation | response to glucose | positive regulation of cell activation | positive regulation of hormone secretion | negative regulation of transport | regulation of protein transport | negative regulation of metabolic process | regulation of peptide transport | negative regulation of transmembrane transport | positive regulation of peptide secretion | response to nitrogen compound | cellular response to hormone stimulus | positive regulation of mononuclear cell proliferation | system development | regulation of fatty acid beta-oxidation | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | cellular response to peptide hormone stimulus | mammary gland development | cellular response to insulin stimulus | regulation of catalytic activity | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | positive regulation of secretion | cellular response to peptide | insulin receptor signaling pathway | positive regulation of cellular metabolic process | regulation of lymphocyte activation | negative regulation of lymphocyte apoptotic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | regulation of cellular component movement | regulation of fatty acid metabolic process | positive regulation of cell migration | negative regulation of ion transmembrane transport | positive regulation of glucose transmembrane transport | cell proliferation | negative regulation of B cell apoptotic process | negative regulation of ion transport | regulation of B cell apoptotic process | cell communication | regulation of cellular metabolic process | regulation of lipid catabolic process | positive regulation of cell proliferation | response to monosaccharide | positive regulation of establishment of protein localization | regulation of locomotion | positive regulation of B cell activation | positive regulation of transport | positive regulation of peptide hormone secretion | negative regulation of lipid transport | regulation of establishment of protein localization | response to organic substance | gland development | positive regulation of fatty acid beta-oxidation | positive regulation of insulin secretion | regulation of kinase activity | positive regulation of fatty acid metabolic process | response to insulin | anatomical structure development | cell surface receptor signaling pathway | regulation of glucose metabolic process | negative regulation of fatty acid transport | positive regulation of glucose metabolic process | positive regulation of leukocyte activation | negative regulation of programmed cell death | regulation of secretion | regulation of glucose transmembrane transport | animal organ development | regulation of cell activation | regulation of protein secretion | regulation of fatty acid oxidation | regulation of phosphate metabolic process | regulation of ion transmembrane transport | positive regulation of protein transport | positive regulation of carbohydrate metabolic process | regulation of cell communication | negative regulation of molecular function | signaling | negative regulation of leukocyte apoptotic process | negative regulation of plasma membrane long-chain fatty acid transport | regulation of cellular ketone metabolic process | regulation of ion transport | regulation of mesenchymal cell proliferation | developmental process | regulation of transport | regulation of B cell proliferation | positive regulation of mesenchymal cell proliferation | regulation of fatty acid transport | response to organonitrogen compound | regulation of glycogen biosynthetic process | regulation of anion transport | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of generation of precursor metabolites and energy | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | positive regulation of cell motility | response to carbohydrate | negative regulation of cell death | positive regulation of signaling | signal transduction | regulation of signaling | regulation of glycogen metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
cell | cytoplasm | protein-containing complex | plasma membrane | cell periphery | cytosol | intracellular | membrane
