QuickView for ITGB2;jsessionid=1494D7B7B98CD46A62AF657F708DBBB9;jsessionid=C9D8656D51A9BFF3C83755B47E5ACFA8;jsessionid=D0A094B5705445E7FD86A5A872938230;jsessionid=F7DC20F45EA6DD2A0B9E625C9F185813;jsessionid=6215635D09B78868DA1CCE06730D8BC7 (gene)

Gene Symbol:

ITGB2 Homo sapiens

Full name:

integrin subunit beta 2

Synonyms:

CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, integrin beta-2, cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor), complement component 3 receptor 3 and 4 subunit, complement receptor C3 beta-subunit, integrin beta chain, beta 2, integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), leukocyte cell adhesion molecule CD18, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C

Genomic Location:

Chr 21: 45130296-45165303

Description:

This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cau...

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This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Cytogenetic Map:

21q22.3

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