QuickView for ITGB4;jsessionid=DF8609880E9E49F85037CB6168F040CF;jsessionid=DC5EB191BE3137AA6250BE30D32B21E3 (gene)

Gene Symbol:

Itgb4 Mus musculus

Full name:

integrin beta 4

Synonyms:

AA407042, C230078O20, CD104, integrin beta-4

Genomic Location:

Chr 11: 115836039-115869725

Description:

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene ...

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Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AACTTT_UNKNOWN ,  NFKAPPAB_01 ,  LYF1_01 ,  MYOD_Q6 ,  NFKB_C ,  CATRRAGC_UNKNOWN ,  AREB6_03 ,  BACH2_01 ,  BACH1_01 ,  E12_Q6 ,  CACCCBINDINGFACTOR_Q6 ,  PAX_Q6 ,  AP1_Q4_01 ,  GGGYGTGNY_UNKNOWN ,  SMTTTTGT_UNKNOWN ,  TGANTCA_AP1_C ,  CAGGTG_E12_Q6 ,  TTGTTT_FOXO4_01 ,  GCANCTGNY_MYOD_Q6 ,  WGGAATGY_TEF1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-93 ,  Predicted Gene Targets for miR-409-5p

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