QuickView for InsP6;jsessionid=2ECBBA699DFE618CD4AADEDA50ED77B8;jsessionid=30BF9F870EBF1079C44D4D387A3BD133 (gene)
- Gene Symbol:
- IPPK
Homo sapiens - Full name:
- inositol-pentakisphosphate 2-kinase
- Synonyms:
- C9orf12, INSP5K2, IP5K, IPK1, bA476B13.1, inositol-pentakisphosphate 2-kinase, IPK1 homolog, bA476B13.1 (novel protein), inositol 1,3,4,5,6-pentakisphosphate 2-kinase, ins(1,3,4,5,6)P5 2-kinase, insP5 2-kinase
- Genomic Location:
- Chr 9: 94415287-94472368
- Description:
-
The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6). InsP6 has a variety of functions, including stimulation of DNA repair, endocytosis, and mRNA export.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
9q22.31
GO Molecular Function
structural molecule activity | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | protein-containing complex scaffold activity | phosphotransferase activity, alcohol group as acceptor | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | inositol pentakisphosphate 2-kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
positive regulation of macromolecule biosynthetic process | regulation of transcription by RNA polymerase I | inositol metabolic process | polyol metabolic process | positive regulation of cellular biosynthetic process | cellular process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | alcohol metabolic process | positive regulation of RNA biosynthetic process | regulation of nucleic acid-templated transcription | organic hydroxy compound metabolic process | phosphorus metabolic process | regulation of gene expression | organophosphate metabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | cellular carbohydrate metabolic process | carbohydrate phosphorylation | biosynthetic process | phosphorylation | carbohydrate metabolic process | phosphate-containing compound metabolic process | regulation of cellular metabolic process | positive regulation of transcription of nucleolar large rRNA by RNA polymerase I | regulation of RNA metabolic process | metabolic process | regulation of RNA biosynthetic process | organic substance metabolic process | positive regulation of transcription by RNA polymerase I | regulation of transcription, DNA-templated | kinase activity | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | inositol phosphorylation | positive regulation of metabolic process | inositol pentakisphosphate 2-kinase activity | cellular metabolic process | inositol phosphate biosynthetic process | inositol phosphate metabolic process | positive regulation of gene expression
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | RNA polymerase I complex | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | transferase complex | membrane-bounded organelle | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | RNA polymerase complex | membrane-enclosed lumen | cytosol | intracellular
