QuickView for JNK2;jsessionid=FF28C9356B252B873B5564EC82FED219;jsessionid=951E1C714772F7AA1EB5DF9BA22C7325 (gene)

Gene Symbol:

Mapk9 Rattus norvegicus

Full name:

mitogen-activated protein kinase 9

Synonyms:

SAPK, mitogen-activated protein kinase 9, MAP kinase 9, MAPK 9, SAPK-alpha, c-Jun N-terminal kinase 2, p54-alpha, stress activated protein kinase alpha II, stress-activated protein kinase JNK2

Genomic Location:

Chr 10: 35353486-35384319

Description:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases are multifunctional proteins. They are involved in a wide variety of cellular processes such as growth, proliferation, differentiation, transcription regulation, and development. They function in stress responses, apoptosis, inflammation and transformation. For examp...

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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases are multifunctional proteins. They are involved in a wide variety of cellular processes such as growth, proliferation, differentiation, transcription regulation, and development. They function in stress responses, apoptosis, inflammation and transformation. For example, this kinase plays a dominant role in mediating proliferation of lung cancer and prostate cancer cells, and in regulation of osmotic stress-induced tight junction disruption. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

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Orthologs:

Homo sapiens ,  Mus musculus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

COMP1_01 ,  STAT5A_04 ,  CEBPDELTA_Q6 ,  POU1F1_Q6 ,  AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  CACTTTG_MIR520G_MIR520H ,  CATTTCA_MIR203 ,  CATGTAA_MIR496 ,  TTANTCA_UNKNOWN ,  GGATTA_PITX2_Q2

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-205 ,  Predicted Gene Targets for miR-93 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-496

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