QuickView for K88dsRBP;jsessionid=E36FB8D2B80A9406A7E46F6E473325C7 (gene)
- Gene Symbol:
- Adar
Rattus norvegicus - Full name:
- adenosine deaminase, RNA-specific
- Synonyms:
- double-stranded RNA-specific adenosine deaminase, DRADA
- Genomic Location:
- Chr 2: 181935246-181956039
- Description:
-
converts adenosine to inosine in double stranded RNA
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines | cation binding | double-stranded RNA adenosine deaminase activity | nucleic acid binding | hydrolase activity | catalytic activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | tRNA-specific adenosine deaminase activity | DNA binding | ion binding | deaminase activity | organic cyclic compound binding | adenosine deaminase activity | metal ion binding | heterocyclic compound binding | RNA binding | double-stranded RNA binding
GO Biological Process
RNA metabolic process | gene silencing by RNA | negative regulation of phosphorylation | response to virus | negative regulation of immune system process | response to cytokine | RNA processing | nuclear export | regulation of programmed cell death | erythrocyte homeostasis | defense response to other organism | establishment of localization | regulation of immune system process | myeloid cell differentiation | small RNA loading onto RISC | negative regulation of cellular process | negative regulation of kinase activity | cell differentiation | defense response | negative regulation of protein phosphorylation | production of small RNA involved in gene silencing by RNA | negative regulation of gene silencing by RNA | regulation of RNA interference | intracellular transport | positive regulation of viral life cycle | cellular process | regulation of gene expression, epigenetic | localization | protein transport | negative regulation of signaling | dsRNA fragmentation | negative regulation of viral life cycle | immune system development | negative regulation of innate immune response | macromolecule localization | regulation of response to cytokine stimulus | negative regulation of apoptotic process | establishment of localization in cell | negative regulation of cellular metabolic process | somatic diversification of immune receptors via somatic mutation | regulation of immune response | regulation of cellular process | regulation of apoptotic process | gene silencing | regulation of metabolic process | production of miRNAs involved in gene silencing by miRNA | protein import into nucleus | positive regulation of viral genome replication | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | protein export from nucleus | RNA modification | response to stimulus | miRNA loading onto RISC involved in gene silencing by miRNA | response to stress | intracellular protein transport | negative regulation of protein kinase activity | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | protein localization to nucleus | hematopoietic progenitor cell differentiation | ncRNA processing | cellular localization | regulation of gene silencing | cellular nitrogen compound metabolic process | negative regulation of viral genome replication | cellular response to organic cyclic compound | negative regulation of metabolic process | hemopoiesis | cellular component assembly | mRNA metabolic process | cellular biosynthetic process | embryo development | macromolecule modification | myeloid cell homeostasis | regulation of nucleic acid-templated transcription | response to nitrogen compound | response to external biotic stimulus | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | positive regulation of viral process | multicellular organism development | negative regulation of catalytic activity | negative regulation of protein kinase activity by regulation of protein phosphorylation | response to dsRNA | regulation of catalytic activity | regulation of phosphorylation | regulation of gene expression | organic substance transport | negative regulation of type I interferon-mediated signaling pathway | gene silencing by miRNA | defense response to virus | regulation of nitrogen compound metabolic process | definitive hemopoiesis | peptide transport | protein localization to organelle | import into nucleus | negative regulation of viral process | homeostasis of number of cells | response to interferon-alpha | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | negative regulation of immune response | hematopoietic stem cell homeostasis | cellular protein-containing complex assembly | protein import | chordate embryonic development | posttranscriptional gene silencing | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | cellular response to dsRNA | homeostatic process | regulation of protein phosphorylation | regulation of cytokine-mediated signaling pathway | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | cellular response to virus | regulation of viral process | negative regulation of gene silencing | protein-containing complex assembly | posttranscriptional gene silencing by RNA | response to organic substance | regulation of innate immune response | regulation of kinase activity | establishment of protein localization to organelle | anatomical structure development | negative regulation of response to cytokine stimulus | metabolic process | regulation of RNA biosynthetic process | negative regulation of RNA interference | base conversion or substitution editing | negative regulation of programmed cell death | cellular protein localization | amide transport | regulation of gene silencing by RNA | adenosine to inosine editing | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | nuclear transport | regulation of type I interferon-mediated signaling pathway | negative regulation of gene expression | animal organ development | negative regulation of cellular protein metabolic process | gene expression | ribonucleoprotein complex assembly | regulation of phosphate metabolic process | establishment of protein localization | transcription, DNA-templated | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | pre-miRNA processing | regulation of transcription, DNA-templated | response to organic cyclic compound | protein localization | cellular macromolecule localization | cellular macromolecule biosynthetic process | response to biotic stimulus | nucleocytoplasmic transport | developmental process | erythrocyte differentiation | innate immune response | ncRNA metabolic process | negative regulation of cytokine-mediated signaling pathway | heterocycle metabolic process | in utero embryonic development | positive regulation of metabolic process | ossification | osteoblast differentiation | ribonucleoprotein complex biogenesis | immune system process | cellular metabolic process | regulation of viral genome replication | mRNA processing | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of cell death | regulation of viral life cycle | negative regulation of cell death | response to other organism | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | supraspliceosomal complex | nucleolus | cytoplasm | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | nuclear speck | ribonucleoprotein complex | spliceosomal complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
