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QuickView for L1CAM;jsessionid=547E4E533BB6D354F31BF5359F0164AE;jsessionid=FB0B3411664D0231566657772BF7731A;jsessionid=E32B8AAF0531AE39F293712785598584 (gene)


Gene Symbol:
L1cam Rattus norvegicus Rattus norvegicus
Full name:
L1 cell adhesion molecule
Synonyms:
Hsas, Hyd, N-CAM L1, NCAML1, NgCAM, neural cell adhesion molecule L1, N-CAM-L1, NCAM-L1, NILE, nerve-growth factor-inducible large external glycoprotein, neuron-glia cell adhesion molecule
Genomic Location:
Chr X: 159784792-159801553
Description:
member of the Ig superfamily of cell adhesion molecules; involved in neuronal cell development; neural cell adhesion molecule expressed in brain; isoform L1cs is a likely alternative splice variant expressed in the peripheral nervous system
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

protein self-association | transmembrane signaling receptor activity | carboxylic acid binding | protein-containing complex binding | signaling receptor binding | sialic acid binding | axon guidance receptor activity | carbohydrate derivative binding | protein domain specific binding | anion binding | signaling receptor activity | identical protein binding | ion binding | integrin binding | cell adhesion molecule binding | protein binding | PDZ domain binding | organic acid binding | small molecule binding

GO Biological Process

regulation of ERK1 and ERK2 cascade | cell morphogenesis | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | regulation of cell development | cell-substrate adhesion | response to hormone | positive regulation of developmental process | response to dexamethasone | cell differentiation | nervous system development | response to drug | cell part morphogenesis | positive regulation of axonogenesis | neurogenesis | positive regulation of cell adhesion | generation of neurons | response to antibiotic | cellular process | localization | cell projection morphogenesis | regulation of calcium-mediated signaling | neuron development | axon guidance | response to growth factor | regulation of neuron projection development | regulation of cell differentiation | cell recognition | regulation of cellular process | positive regulation of cell growth | cellular response to lipid | regulation of metabolic process | response to nerve growth factor | cellular response to organonitrogen compound | cellular component organization | response to transforming growth factor beta | response to stimulus | cell morphogenesis involved in neuron differentiation | cell adhesion mediated by integrin | cellular response to xenobiotic stimulus | neuron projection guidance | axon guidance receptor activity | positive regulation of cell-cell adhesion | response to alcohol | cellular response to toxic substance | cellular response to ethanol | cellular response to organic cyclic compound | regulation of cellular component size | regulation of axon extension | regulation of cell adhesion | response to ethanol | locomotion | response to nitrogen compound | cellular response to hormone stimulus | system development | cellular response to thyroxine stimulus | regulation of signal transduction | positive regulation of neuron projection development | cellular response to antibiotic | multicellular organism development | response to activity | cell migration | regulation of MAPK cascade | response to amino acid | regulation of axonogenesis | cell-cell adhesion mediated by integrin | cellular response to nerve growth factor stimulus | regulation of phosphorylation | regulation of neuron differentiation | axon development | response to ketone | response to lipid | neuron recognition | regulation of nitrogen compound metabolic process | regulation of cell-substrate adhesion | positive regulation of cell projection organization | positive regulation of intracellular signal transduction | response to corticosteroid | axonal fasciculation | synapse organization | axonogenesis | positive regulation of cell differentiation | positive regulation of calcium-mediated signaling | regulation of cellular protein metabolic process | cellular response to glucocorticoid stimulus | response to toxic substance | response to xenobiotic stimulus | cellular response to amino acid stimulus | cell morphogenesis involved in differentiation | cellular response to corticosteroid stimulus | cellular response to drug | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | neuron projection fasciculation | cellular response to transforming growth factor beta stimulus | positive regulation of axon extension | neuron differentiation | cellular response to thyroid hormone stimulus | regulation of cell morphogenesis involved in differentiation | regulation of growth | response to organic substance | response to L-phenylalanine derivative | response to antineoplastic agent | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | leukocyte cell-cell adhesion | cell projection organization | positive regulation of cell development | cell adhesion | neuron projection development | positive regulation of cell-substrate adhesion | regulation of phosphate metabolic process | cellular response to steroid hormone stimulus | cell-cell adhesion | dopaminergic neuron differentiation | cellular response to dexamethasone stimulus | regulation of cell communication | positive regulation of developmental growth | signaling | positive regulation of growth | cell-matrix adhesion | response to organic cyclic compound | cell development | regulation of developmental growth | regulation of cell size | anatomical structure morphogenesis | regulation of nervous system development | regulation of developmental process | developmental process | regulation of cell growth | response to thyroid hormone | regulation of cell-cell adhesion | response to organonitrogen compound | response to thyroxine | cell-cell adhesion via plasma-membrane adhesion molecules | positive regulation of neuron differentiation | regulation of cell projection organization | cellular response to organic substance | response to steroid hormone | positive regulation of cell morphogenesis involved in differentiation | chemotaxis | regulation of cellular component organization | homotypic cell-cell adhesion | positive regulation of signaling | signal transduction | regulation of signaling | response to glucocorticoid | cellular response to growth factor stimulus | homophilic cell adhesion via plasma membrane adhesion molecules | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

presynaptic membrane | integral component of membrane | dendrite | synapse | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | neuronal cell body | distal axon | dendrite terminus | intrinsic component of membrane | synaptic membrane | terminal bouton | external side of plasma membrane | cytoplasm | intracellular organelle | membrane microdomain | dendritic tree | presynapse | cell projection | endomembrane system | plasma membrane | membrane raft | vesicle | site of polarized growth | axonal growth cone | endosome | membrane-bounded organelle | organelle | axon terminus | cell periphery | axon | growth cone | neuron projection terminus | intracellular vesicle | cell surface | dendritic growth cone | intracellular | membrane