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QuickView for LLGL1;jsessionid=FC440CFD29809F033A3EBB5DD9B1EA47 (gene)


Gene Symbol:
l(2)gl D. melanogaster D. melanogaster
Full name:
lethal (2) giant larvae
Synonyms:
CG2671, D-LGL, dlgl, DmelCG2671, Dmel_CG2671, gl, l(2), l(2) giant larva, l(2)giant larvae, l(2)gl, l(2)gl, L(2)GL, l-gl, LGL, l[[2]]gl, p127, p127l(2)gl
Genomic Location:
Chr 2L: 9836-21372
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

enzyme activator activity | protein kinase regulator activity | GTPase binding | kinase regulator activity | protein kinase inhibitor activity | GTPase activator activity | enzyme binding | syntaxin binding | enzyme inhibitor activity | GTPase regulator activity | myosin binding | Ras GTPase binding | molecular function regulator | cytoskeletal protein binding | myosin II binding | protein binding | kinase inhibitor activity | small GTPase binding | Rab GTPase binding | SNARE binding | enzyme regulator activity

GO Biological Process

synaptic vesicle exocytosis | negative regulation of phosphorylation | molting cycle | embryonic development via the syncytial blastoderm | actin filament-based process | exocytosis | microtubule cytoskeleton organization involved in mitosis | epidermis morphogenesis | regulation of cell morphogenesis | regulation of neurogenesis | neurotransmitter secretion | developmental process involved in reproduction | protein localization to cell periphery | enzyme activator activity | regulation of cell development | establishment or maintenance of polarity of embryonic epithelium | salivary gland cell autophagic cell death | ecdysone-mediated induction of salivary gland cell autophagic cell death | regulation of localization | larval development | protein kinase regulator activity | morphogenesis of an epithelium | establishment of epithelial cell planar polarity | regulation of programmed cell death | actin cytoskeleton organization | larval chitin-based cuticle development | establishment of localization | response to hormone | negative regulation of neuroblast proliferation | regulation of cell shape | negative regulation of cellular process | negative regulation of kinase activity | microtubule cytoskeleton organization | establishment of mitotic spindle orientation | cell differentiation | nervous system development | negative regulation of protein phosphorylation | neurogenesis | post-embryonic animal organ morphogenesis | establishment or maintenance of apical/basal cell polarity | anatomical structure regression | generation of neurons | salivary gland morphogenesis | intracellular transport | regulation of neuroblast proliferation | microtubule-based process | molting cycle, chitin-based cuticle | pattern specification process | positive regulation of GTPase activity | cellular process | secretion | establishment of organelle localization | localization | epithelial tube morphogenesis | imaginal disc morphogenesis | cell maturation | basal protein localization | symmetric cell division | negative regulation of signaling | chemical synaptic transmission | kinase regulator activity | establishment or maintenance of microtubule cytoskeleton polarity | protein kinase inhibitor activity | multicellular organismal reproductive process | GTPase activator activity | macromolecule localization | regulation of cell cycle | establishment of mitotic spindle localization | response to growth factor | positive regulation of catalytic activity | establishment or maintenance of polarity of follicular epithelium | establishment of localization in cell | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | gamete generation | oocyte anterior/posterior axis specification | cell junction assembly | maternal determination of anterior/posterior axis, embryo | morphogenesis of a polarized epithelium | regulation of cellular process | regulation of metabolic process | organelle localization | cortical actin cytoskeleton organization | epithelium development | establishment of cell polarity | cellular component organization | cell competition in a multicellular organism | response to transforming growth factor beta | asymmetric neuroblast division | response to stimulus | enzyme inhibitor activity | female gamete generation | metamorphosis | GTPase regulator activity | gland morphogenesis | germ cell development | negative regulation of protein kinase activity | regulation of cell proliferation | establishment of spindle localization | response to ecdysone | tube morphogenesis | programmed cell death | reproduction | cellular localization | secretion by cell | response to alcohol | instar larval or pupal development | cuticle development | blastoderm segmentation | negative regulation of metabolic process | cellular component assembly | embryo development | cell-cell signaling | molecular function regulator | regulation of establishment or maintenance of cell polarity | anterior/posterior pattern specification | somatic stem cell division | oocyte construction | regulation of neurotransmitter levels | synaptic vesicle cycle | system development | reproductive process | regulation of signal transduction | establishment of neuroblast polarity | post-embryonic animal organ development | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | neuroblast proliferation | oocyte microtubule cytoskeleton organization | spindle localization | regulation of catalytic activity | oocyte differentiation | regulation of phosphorylation | asymmetric protein localization involved in cell fate determination | localization within membrane | morphogenesis of larval imaginal disc epithelium | stem cell proliferation | response to ketone | response to lipid | cell cycle | synaptic signaling | embryonic axis specification | regulation of stem cell proliferation | stem cell division | animal organ morphogenesis | synaptic vesicle priming | regulation of nitrogen compound metabolic process | regulation of Notch signaling pathway | enzyme linked receptor protein signaling pathway | apical junction assembly | post-embryonic animal morphogenesis | vesicle-mediated transport | oogenesis | establishment or maintenance of neuroblast polarity | positive regulation of hydrolase activity | establishment of spindle orientation | chitin-based larval cuticle pattern formation | establishment or maintenance of polarity of larval imaginal disc epithelium | establishment of vesicle localization | cell proliferation | cell division | neuronal stem cell division | regulation of cellular protein metabolic process | regulated exocytosis | cellular protein-containing complex assembly | epidermis development | regulation of GTPase activity | cuticle pattern formation | programmed cell death involved in cell development | instar larval development | post-embryonic development | establishment or maintenance of cell polarity | sensory organ development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | transmembrane receptor protein serine/threonine kinase signaling pathway | anterior/posterior axis specification | asymmetric cell division | regulation of protein metabolic process | negative regulation of stem cell proliferation | apical protein localization | regulation of protein phosphorylation | chitin-based cuticle development | embryo development ending in birth or egg hatching | embryonic morphogenesis | positive regulation of molecular function | autophagic cell death | cellular response to transforming growth factor beta stimulus | multicellular organism reproduction | protein-containing complex assembly | regionalization | axis specification | regulation of growth | response to organic substance | gland development | tissue morphogenesis | kinase inhibitor activity | regulation of kinase activity | regulation of exocytosis | anatomical structure development | protein localization to cell cortex | mitotic cell cycle | cell surface receptor signaling pathway | regulation of neural precursor cell proliferation | cell fate commitment | dorsal closure | cell-cell junction assembly | oocyte axis specification | developmental maturation | establishment or maintenance of epithelial cell apical/basal polarity | salivary gland histolysis | cellular protein localization | imaginal disc development | regulation of vesicle-mediated transport | calcium ion regulated exocytosis | regulation of secretion | positive regulation of cell death | morphogenesis of embryonic epithelium | cell death | animal organ development | establishment of epithelial cell polarity | negative regulation of cellular protein metabolic process | anterior/posterior axis specification, embryo | positive regulation of programmed cell death | neural precursor cell proliferation | regulation of phosphate metabolic process | cytoskeleton organization | establishment of protein localization | oocyte development | transforming growth factor beta receptor signaling pathway | neuroblast division | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | response to organic cyclic compound | cell development | synaptic vesicle localization | protein localization | enzyme regulator activity | anatomical structure morphogenesis | cellular macromolecule localization | regulation of nervous system development | regulation of developmental process | segmentation | developmental process | septate junction assembly | organelle organization | cortical cytoskeleton organization | tube development | regulation of transport | negative regulation of cell proliferation | negative regulation of neural precursor cell proliferation | morphogenesis of follicular epithelium | neurotransmitter transport | cell fate determination | signal release | asymmetric stem cell division | establishment or maintenance of cytoskeleton polarity | vesicle localization | negative regulation of Notch signaling pathway | synaptic vesicle transport | cellular response to organic substance | exocrine system development | regulation of cell death | salivary gland development | negative regulation of cell development | sexual reproduction | negative regulation of cell differentiation | regulation of cellular component organization | signal transduction | regulation of signaling | embryonic pattern specification | cellular response to growth factor stimulus | negative regulation of neurogenesis | multicellular organismal process | cell-cell junction organization | regulation of phosphorus metabolic process

GO Cellular Component

occluding junction | exocytic vesicle | synapse | extracellular matrix | cytoplasmic vesicle | cell | cytoplasm | cortical cytoskeleton | smooth septate junction | intracellular organelle | actin cytoskeleton | presynapse | cell-cell junction | secretory vesicle | endomembrane system | plasma membrane | vesicle | transport vesicle | cytoplasmic region | synaptic vesicle | cortical actin cytoskeleton | extracellular region | cell cortex | membrane-bounded organelle | apicolateral plasma membrane | apical junction complex | organelle | cell periphery | basolateral plasma membrane | septate junction | cytosol | intracellular vesicle | cytoskeleton | intracellular | cell junction | membrane