QuickView for LNPEP;jsessionid=80394BD58223DA521C70898CF2676171 (gene)
- Gene Symbol:
- Lnpep
Rattus norvegicus - Full name:
- leucyl and cystinyl aminopeptidase
- Synonyms:
- IRAP, P-LAP, Vp165, leucyl-cystinyl aminopeptidase, GP160, OTase, aminopeptidase Vp165, angiotensin IV receptor, cystinyl aminopeptidase, insulin-regulated membrane aminopeptidase IRAP, insulin-responsive aminopeptidase, leucyl/cystinyl aminopeptidase, oxytocinase, placental leucine aminopeptidase, vesicle protein of 165 kDa
- Genomic Location:
- Chr 1: 56071820-56151257
- Description:
-
a zinc-dependent aminopeptidase that interacts with acyl-coenzyme A (CoA) dehydrogenases and plays a role in retention of GLUT4-containing vesicles to an intracellular compartment
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
metallopeptidase activity | peptide binding | peptide hormone binding | cation binding | transmembrane signaling receptor activity | G-protein coupled receptor activity | hydrolase activity | catalytic activity | exopeptidase activity | amide binding | signaling receptor activity | ion binding | metalloexopeptidase activity | hormone binding | zinc ion binding | aminopeptidase activity | metalloaminopeptidase activity | transition metal ion binding | angiotensin receptor activity | peptide receptor activity | G-protein coupled peptide receptor activity | metal ion binding | peptidase activity
GO Biological Process
metallopeptidase activity | SMAD protein signal transduction | proteolysis | response to hormone | cellular process | organic substance catabolic process | regulation of neuronal synaptic plasticity | response to peptide hormone | regulation of cellular process | catabolic process | cellular response to organonitrogen compound | G-protein coupled receptor activity | response to stimulus | positive regulation of blood pressure | neuropeptide catabolic process | response to peptide | cellular nitrogen compound metabolic process | blood circulation | G-protein coupled receptor signaling pathway | modulation of chemical synaptic transmission | response to nitrogen compound | regulation of long-term neuronal synaptic plasticity | cellular response to hormone stimulus | nitrogen compound metabolic process | cellular response to peptide hormone stimulus | cellular response to peptide | protein catabolic process | regulation of blood pressure | exopeptidase activity | enzyme linked receptor protein signaling pathway | cellular amide metabolic process | cellular response to angiotensin | metalloexopeptidase activity | angiotensin-activated signaling pathway | cell communication | transmembrane receptor protein serine/threonine kinase signaling pathway | peptide metabolic process | response to angiotensin | aminopeptidase activity | protein metabolic process | response to organic substance | peptide catabolic process | cell surface receptor signaling pathway | metalloaminopeptidase activity | metabolic process | organic substance metabolic process | angiotensin receptor activity | organonitrogen compound catabolic process | regulation of cell communication | signaling | G-protein coupled peptide receptor activity | response to organonitrogen compound | regulation of synaptic plasticity | cellular metabolic process | peptidase activity | cellular response to organic substance | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
secretory granule | integral component of membrane | intracellular membrane-bounded organelle | somatodendritic compartment | organelle membrane | cytoplasmic vesicle | cell body | cell | neuronal cell body | intrinsic component of membrane | cytoplasm | intracellular organelle | secretory vesicle | endomembrane system | plasma membrane | vesicle | perinuclear region of cytoplasm | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | insulin-responsive compartment | intracellular vesicle | cell surface | intracellular | membrane | cytoplasmic vesicle membrane
