QuickView for MD2;jsessionid=272E977E17C48CB3CC6D5283E6C854F2;jsessionid=AF234F68E2C5174F9905FC1FCA3B30DD (gene)

Gene Symbol:

LY96 Homo sapiens

Full name:

lymphocyte antigen 96

Synonyms:

ESOP-1, MD-2, MD2, ly-96, lymphocyte antigen 96, myeloid differentiation protein-2, protein MD-2

Genomic Location:

Chr 8: 75066144-75103859

Description:

This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple tr...

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This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Cytogenetic Map:

8q21.11

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