QuickView for MDH;jsessionid=6E526EA1795F20D979BA8AF338567F39;jsessionid=7BB404A108041079CD16FC9BD2C508E6;jsessionid=4BBA7DBB0F6F7CDF8958DBEE4150DDFA;jsessionid=5B3641C3320EB6E7D6C39A8A7EC10D7A (gene)
- Gene Symbol:
- Me1
Rattus norvegicus - Full name:
- malic enzyme 1
- Synonyms:
- MOD1, NADP-dependent malic enzyme, NADP-ME, cytosolic malic enzyme 1, malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+), malic enzyme 1, NADP(+)-dependent, cytosolic, malic enzyme 1, soluble
- Genomic Location:
- Chr 8: 91841160-91955917
- Description:
-
catalyzes the NADP+ dependent conversion of S-malate to pyruvate
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
| Protein Names |
|---|
| No proteins found. |
GO Molecular Function
oxidoreductase activity, acting on CH-OH group of donors | NADP binding | cofactor binding | malic enzyme activity | cation binding | oxaloacetate decarboxylase activity | nucleotide binding | coenzyme binding | lyase activity | carbon-carbon lyase activity | catalytic activity | malate dehydrogenase activity | carboxy-lyase activity | ion binding | organic cyclic compound binding | manganese ion binding | NAD binding | transition metal ion binding | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | malate dehydrogenase (decarboxylating) (NAD+) activity | malate dehydrogenase (decarboxylating) (NADP+) activity | metal ion binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
oxidoreductase activity, acting on CH-OH group of donors | response to hormone | malic enzyme activity | cellular process | dicarboxylic acid metabolic process | regulation of cellular process | regulation of metabolic process | cellular component organization | response to stimulus | monocarboxylic acid metabolic process | malate metabolic process | cellular component assembly | malate dehydrogenase activity | protein complex oligomerization | regulation of nitrogen compound metabolic process | small molecule metabolic process | pyruvate metabolic process | protein tetramerization | regulation of cellular metabolic process | carboxylic acid metabolic process | protein-containing complex assembly | response to organic substance | metabolic process | oxidation-reduction process | organic substance metabolic process | regulation of phosphate metabolic process | organic acid metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | malate dehydrogenase (decarboxylating) (NAD+) activity | malate dehydrogenase (decarboxylating) (NADP+) activity | cellular metabolic process | oxidoreductase activity | regulation of NADP metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | cytosol | intracellular
