QuickView for METTL3;jsessionid=CCC6CC707DE4D4D530E7307B534F5B4C;jsessionid=955EF05860B0719CC005C91360BD79A9 (gene)
- Gene Symbol:
- mettl3
Danio rerio - Full name:
- methyltransferase like 3
- Synonyms:
- fj82g07, MGC77093, wu:fj82g07, zgc:77093
- Genomic Location:
- Chr 7: 19608823-19619346
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , Saccharomyces cerevisiae , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity | nucleic acid binding | S-adenosylmethionine-dependent methyltransferase activity | mRNA binding | coenzyme binding | catalytic activity | protein heterodimerization activity | organic cyclic compound binding | S-adenosyl-L-methionine binding | mRNA methyltransferase activity | protein binding | protein dimerization activity | transferase activity | RNA methyltransferase activity | mRNA (N6-adenosine)-methyltransferase activity | drug binding | methyltransferase activity | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | gene silencing by RNA | brain development | Notch signaling pathway | response to radiation | cell morphogenesis | forebrain radial glial cell differentiation | positive regulation of macromolecule biosynthetic process | Notch signaling pathway involved in arterial endothelial cell fate commitment | RNA processing | regulation of mRNA modification | cell motility | developmental process involved in reproduction | regulation of programmed cell death | regulation of meiotic cell cycle | regulation of immune system process | negative regulation of cellular process | cell differentiation | regulation of T cell differentiation | endothelial cell differentiation | male gamete generation | nervous system development | regulation of hematopoietic progenitor cell differentiation | production of small RNA involved in gene silencing by RNA | neurogenesis | generation of neurons | flagellated sperm motility | positive regulation of cellular biosynthetic process | cellular process | regulation of gene expression, epigenetic | organic substance catabolic process | primary miRNA methylation | localization | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity | cell maturation | negative regulation of signaling | dsRNA fragmentation | immune system development | delamination | multicellular organismal reproductive process | stem cell population maintenance | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | gamete generation | positive regulation of mRNA catabolic process | regulation of mRNA stability | regulation of cellular process | regulation of apoptotic process | gene silencing | regulation of metabolic process | gliogenesis | catabolic process | production of miRNAs involved in gene silencing by miRNA | S-adenosylmethionine-dependent methyltransferase activity | organic cyclic compound metabolic process | positive regulation of translation | positive regulation of cellular protein metabolic process | epithelium development | cellular aromatic compound metabolic process | cellular component organization | mRNA catabolic process | response to UV | head development | regulation of translational initiation | RNA modification | blood vessel endothelial cell differentiation | response to stimulus | RNA splicing | vasculature development | female gamete generation | RNA methylation | positive regulation of protein metabolic process | negative regulation of cell adhesion | cellular response to light stimulus | response to stress | RNA splicing, via transesterification reactions | germ cell development | posttranscriptional regulation of gene expression | sperm motility | ncRNA processing | reproduction | cardiovascular system development | cellular nitrogen compound metabolic process | mRNA modification | cellular response to organic cyclic compound | negative regulation of metabolic process | hemopoiesis | mRNA metabolic process | regulation of cell adhesion | macromolecule modification | nucleobase-containing compound catabolic process | regulation of lymphocyte differentiation | blood vessel development | primary miRNA processing | locomotion | response to nitrogen compound | endothelial to hematopoietic transition | response to light stimulus | epithelial cell fate commitment | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | endothelium development | multicellular organism development | response to dsRNA | cellular response to DNA damage stimulus | oocyte differentiation | regulation of T cell activation | regulation of hematopoietic stem cell differentiation | regulation of gene expression | stem cell proliferation | methylation | cellular response to stress | gene silencing by miRNA | RNA catabolic process | positive regulation of cellular metabolic process | regulation of lymphocyte activation | cellular response to radiation | regulation of nitrogen compound metabolic process | regulation of Notch signaling pathway | regulation of RNA stability | oogenesis | radial glial cell differentiation | cell proliferation | regulation of cellular protein metabolic process | glial cell differentiation | sex determination | cell morphogenesis involved in differentiation | positive regulation of cap-independent translational initiation | cellular response to UV | negative regulation of cell-cell adhesion | mRNA destabilization | posttranscriptional gene silencing | cell communication | regulation of cellular metabolic process | hematopoietic stem cell proliferation | arterial endothelial cell fate commitment | regulation of protein metabolic process | mRNA methyltransferase activity | aromatic compound catabolic process | cellular response to dsRNA | regulation of RNA metabolic process | regulation of stem cell differentiation | positive regulation of cytoplasmic translational initiation | positive regulation of translational initiation | multicellular organism reproduction | posttranscriptional gene silencing by RNA | response to organic substance | regulation of hemopoiesis | mRNA methylation | cellular macromolecule catabolic process | anatomical structure development | cell surface receptor signaling pathway | metabolic process | cell fate commitment | developmental maturation | base conversion or substitution editing | forebrain generation of neurons | adenosine to inosine editing | nucleobase-containing compound metabolic process | organic substance metabolic process | maintenance of cell number | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | regulation of mRNA catabolic process | forebrain development | negative regulation of cellular protein metabolic process | gene expression | regulation of cell activation | RNA destabilization | positive regulation of cytoplasmic translation | negative regulation of translation | regulation of cytoplasmic translation | oocyte development | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of signal transduction | signaling | response to organic cyclic compound | RNA methyltransferase activity | cell development | mRNA (N6-adenosine)-methyltransferase activity | anatomical structure morphogenesis | regulation of developmental process | methyltransferase activity | developmental process | arterial endothelial cell differentiation | spermatogenesis | regulation of cell-cell adhesion | ncRNA metabolic process | epithelial cell differentiation | oocyte maturation | heterocycle metabolic process | central nervous system development | positive regulation of metabolic process | immune system process | negative regulation of Notch signaling pathway | cellular metabolic process | mRNA processing | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of cell death | regulation of translation | circulatory system development | sexual reproduction | mRNA splicing, via spliceosome | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
mRNA editing complex | intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | cytoplasm | intracellular organelle | RNA N6-methyladenosine methyltransferase complex | nuclear body | protein-containing complex | methyltransferase complex | nucleoplasm | nuclear speck | transferase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
